Center for Health Equity and Quality Research (CHEQR) Lectures

Lectures and Courses

Foundation and Health Services Grants

Foundation and Health Services Grants by Lori Bilello, MBA/MHS, PhD and Sarah Osian, PhD. This lecture reviews the different types of federal, state, local and foundation grants available. It also discusses the major components to be addressed for these grants and some of the challenges and advantages in pursing these types of grants.

PCORI Grants

PCORI Grant Writing Skills by Thomas Pearson, MD, MPH PhD. This lecture describes the focus of PCOR grants – Patient Centered Outcomes Research and the requirements to be comparative effectiveness research. It also reviews the different funding announcements available and the basic requirements for a successful grant.

Research Study Design

This is a 12-part course based on the book "Designing Clinical Research" by Hulley and Cummings (4th Edition). It is recommended that you order the book and read the chapters corresponding to the lectures prior to listening to the presentations. The corresponding chapters are listed on the syllabus below. Each lecture is approximately one hour in length. Do note that there is no video recorded lecture for week 12.

Research Study Design Course Syllabus .pdf (Adobe PDF Document)

Part 1 - Anatomy and Physiology of Research - The Research Question

Part 1 - Anatomy and Physiology of Research - The Research Question

Presentation: Part 1 - Presentation .pdf (Adobe PDF Document)

Part 2 - Choosing Study Subject and Planning Study Measurements

Part 2 - Choosing Study Subject and Planning Study Measurements

Presentation: Part 2 - Presentation .pdf (Adobe PDF Document)

Part 3 - Sample Size Estimates

Part 3 - Sample Size Estimates

Presentation: Part 3 - Presentation .pdf (Adobe PDF Document)

Part 4 - Clinical Trial Designs

Part 4 - Clinical Trial Designs

Presentation: Part 4 - Presentation .pdf (Adobe PDF Document)

Attachments: Emerging Treatments and Technologies Original Article - 6 Month Study on Effects of Protein Kinase... .pdf (Adobe PDF Document), Study Designs for PDSA Quality Improvement Research .pdf (Adobe PDF Document), Research Innovations and Recommendations - Alternatives to the Randomized Controlled Trial .pdf (Adobe PDF Document)

Part 5 - Studies of Diagnostic Tests

Part 5 - Studies of Diagnostic Tests

Presentation: Part 5 - Presentation .pdf (Adobe PDF Document)

Attachments: ROC Curve Example .pdf (Adobe PDF Document)

Part 6 - Case-Control Study Designs

Part 6 - Case-Control Study Designs

Presentation: Part 6 - Presentation .pdf (Adobe PDF Document)

Part 7 - Large Dataset Studies

Part 7 - Large Dataset Studies

Presentation: Part 7 - Presentation .pdf (Adobe PDF Document)

Part 8 - Study Conduct, IRB and Data Management

Part 8 - Study Conduct, IRB and Data Management

Presentation: Part 8 - Presentation .pdf (Adobe PDF Document)

Part 9 - Designing Questionnaires and Interviews

Part 9 - Designing Questionnaires and Interviews

Presentation: Part 9 - Presentation .pdf (Adobe PDF Document)

Part 10 - Cohort Study Design

Part 10 - Cohort Study Design

Presentation: Part 10 - Presentation .pdf (Adobe PDF Document)

Part 11 - Enhancing Casual Inference

Part 11 - Enhancing Casual Inference

Presentation: Part 11 - Presentation .pdf (Adobe PDF Document)

Part 12 - Design and Methods for T3 and T4 Studies We apologize, but there is no video recorded lecture for Week 12.

Presentation: Part 12 - Presentation .pdf (Adobe PDF Document)

Biostatistics

This is a 12 part course that covers basic statistical concepts and procedures for clinical research. The recommended text is Basic & Clinical Biostatistics by Apple & Lange (4th Edition). Each lecture is approximately one hour in length. The statistical software package that is used in lecture examples is SPSS. If you do not have SPSS, please contact the Office of Research Affairs on how to purchase this software for a nominal fee.

Biostatistics Course Syllabus .pdf (Adobe PDF Document)

Part 1 - Probability and Data Types

Part 1 - Probability and Data Types

Presentation: Part 1 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 1 Handout .pdf (Adobe PDF Document)

Part 2 - Graphical and Numerical Summaries

Part 2 - Graphical and Numerical Summaries

Presentation: Part 2 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 2 Handout .pdf (Adobe PDF Document)

Part 3 - Hypothesis Testing - 1 Sample Tests

Part 3 - Hypothesis Testing - 1 Sample Tests

Presentation: Part 3 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 3 Handout .pdf (Adobe PDF Document)

Part 4 - 2 Sample Tests

Part 4 - 2 Sample Tests

Presentation: Part 4 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 4 Handout .pdf (Adobe PDF Document)

Part 5 - More Than 2 Sample Tests

Part 5 - More Than 2 Sample Tests

Presentation: Part 5 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 5 Handout .pdf (Adobe PDF Document)

Part 6 - Time to Event Data

Part 6 - Time to Event Data

Presentation: Part 6 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 6 Handout .pdf (Adobe PDF Document), SAS Lifetest Example .pdf (Adobe PDF Document)

Part 7 - Associations, Correlation and Regression I

Part 7 - Associations, Correlation and Regression I

Presentation: Part 7 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 7 Handout .pdf (Adobe PDF Document)

Part 8 - Regression II

Part 8 - Regression II

Presentation: Part 8 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 8 Handout .pdf (Adobe PDF Document), Multicollinearity Example Output .pdf (Adobe PDF Document), Variable Selection Handout .pdf (Adobe PDF Document)

Part 9 - Bayes Theorem - Diagnostic Tests

Part 9 - Bayes Theorem - Diagnostic Tests

Presentation: Part 9 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 9 Handout .pdf (Adobe PDF Document)

Part 10 - Correlated Data

Part 10 - Correlated Data

Presentation: Part 10 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Nested ANOVA Handout .pdf (Adobe PDF Document), Repeated Measures ANOVA Handout .pdf (Adobe PDF Document)

Part 11 - Meta-Analysis

Part 11 - Meta-Analysis

Presentation: Part 11 - Presentation .pdf (Adobe PDF Document)

Part 12 - Effect Sizes, Confidence Intervals, Etc.

Part 12 - Effect Sizes, Confidence Intervals, Etc.

Presentation: Part 12 - Presentation .pdf (Adobe PDF Document)

Handouts & Attachments: Week 12 Handout .pdf (Adobe PDF Document), Confidence Intervals Handout .pdf (Adobe PDF Document), Cox PH Model Handout .pdf (Adobe PDF Document), Logistic Regression Example Handout .pdf (Adobe PDF Document), Regression Estimates Handout .pdf (Adobe PDF Document), Two Factor ANOVA Handout .pdf (Adobe PDF Document)