Created in 1971, the practice plan was established as a separate 501(c)(3) non-profit corporation in 1979 and named the University of Florida Jacksonville Physicians, Inc. (UFJPI). The members of the practice plan are physician employees of the University of Florida and hold academic or clinical appointments.

A number of services are provided to include credentialing of providers, training in medical coding to staff and physicians, fee schedule analysis, compliance education and testing for Medicare, Medicaid and other programs. In addition, managed care services, information systems support, finance and accounting and human resource services are provided by UFJPI.