Clinical Research Details Clinical Research Researching Precision Emergency Asthma Treatment (RePEAT): Pharmacogenomics of Bronchodilator Response Study Description This study is a first step in a larger research goal to bring precision medicine to emergency care for children with asthma. We will enroll African American patients from the UF Jacksonville Pediatric Emergency Department and collect clinical data including bronchodilator response (BDR). We will test whether 21 single nucleotide polymorphisms identified in previous studies are associated with BDR when it matters most, during an asthma exacerbation. Inclusion/Exclusion Criteria Inclusion Criteria Ages 2-18 Pediatric patient arriving to UF-Jax Pediatric ED with prior diagnosis of asthma or ED Physician confirmation of asthma. Legal guardian present for patients ages 2-17 Exclusion Criteria Cystic fibrosis or bronchopulmonary dysplasia Law enforcement custody Pregnant Foster children/ wards of the state. Non- English speaking Critically ill patients that this study would be a burden to care. (patients with an acuity of 1 or at the discretion of the treating team) Investigators Jennifer N. Fishe, M.D. Emergency Medicine