Clinical Research Details Clinical Research A Multicenter, Interventional, Retrospective and Prospective study of Enzyme Replacement Therapy (VPRIV) Clinical Outcomes and Safety in Gaucher Disease Type 1 Patients Previously Treated with Substrate Reduction Therapy Study Description Adult patients with Gaucher Disease Type 1 who have previously received SRT (substrate replacement therapy) and are now receiving ERT (enzyme replacement therapy) with velaglucerase alfa. For group B, no visits are required since this is a retrospective data collection. For group A, there are visits every 3 months for 1 year. These will include drawing blood, using an app on your cell phone to answer questionnaires, and an interview at the end of the study. Inclusion/Exclusion Criteria Adult patients with Gaucher Disease Type 1 who have previously received SRT (substrate replacement therapy) and are now receiving ERT (enzyme replacement therapy) with velaglucerase alfa. Investigators Estrella Lizbeth Mellin Sanchez, M.D. Pediatrics