Dominick J. Angiolillo, M.D., Ph.D., FACC

Dominick J. Angiolillo M.D., Ph.D., FACC

Professor & Chief, Division of Cardiology; Medical Director, UF Health Cardiovascular Center - Jacksonville; Medical Director, Cardiovascular Research Program; Program Director, Interventional Cardiology Fellowship

Department: Department of Medicine
Business Phone: (904) 244-2655

About Dominick J. Angiolillo

Dominick Angiolillo, M.D., Ph.D., graduated summa cum laude from the Catholic University of the Sacred Heart Medical School in Rome, Italy, where he completed training in medicine and cardiology. He then pursued training in interventional cardiology at the Complutense University of Madrid in Spain and received his Ph.D. in cellular and molecular cardiology. In 2004, Dr. Angiolillo joined the University of Florida College of Medicine – Jacksonville, where he is a professor of medicine with tenure status, director of cardiovascular research and director of the interventional cardiology fellowship program. He is staff cardiologist and interventional cardiologist on the UF Health Jacksonville campus. Dr. Angiolillo is board-certified in internal medicine, cardiovascular disease and interventional cardiology.

Much of Dr. Angiolillo’s professional career has been devoted to cardiovascular research in the field of interventional cardiology and acute coronary syndrome. His largest national and international recognition has been for his pivotal contributions in the field of thrombosis. In particular, Dr. Angiolillo has performed seminal studies on platelet function and modulation of antiplatelet drug response, including genetic studies. He has received national and international academic recognitions for this work. Recognitions include the 2013 Outstanding Achievement Award from the European Society of Cardiology and, since 2014, Dr. Angiolillo has been in the top 1 percent of most-cited researchers worldwide, according to Clarivate Analytics. Dr. Angiolillo has been a key investigator in the clinical development of numerous novel antithrombotic agents. He works alongside drug-regulating agencies in the United States and Europe toward approval of these drugs and product labeling updates. His success in obtaining extramural funding has allowed the development of one of the most active clinical research centers in the U.S. as well as one of the leading centers for thrombosis research in the world.

Dr. Angiolillo has made major scientific contributions to many medical and cardiovascular journals, as well as cardiovascular medicine textbooks. He has authored more than 400 peer-reviewed articles, with nearly 30,000 citations and an H-index of 86. He has authored more than 30 book chapters and is the editor of his own textbook on antithrombotic medicine. Due to his major contributions in antithrombotic therapy in patients with cardiovascular disease manifestations, Dr. Angiolillo has been invited to deliver lectures worldwide. His international visibility has allowed him to develop a very active research training program, attracting physicians and scientists from across the globe. In addition, Dr. Angiolillo has been a clinical mentor for years to residents and fellows, resulting in several Exemplary Teacher Awards. His leadership role as an academic clinician and scientist allows to him to nurture and promote career growth of many young trainees in the United States and abroad.

Dr. Angiolillo is an active member of many cardiovascular societies in the U.S. and Europe. In addition, he serves on the editorial board of numerous cardiovascular journals, some of which he holds leadership roles. He is a scientific reviewer for many major journals and extramural funding agencies, including the National Institutes of Health and other federal funding agencies in several European countries.

Board Certifications

  • Cardiovascular Disease
  • Interventional Cardiology

Clinical Profile

  • Cardiovascular Disease
  • Interventional Cardiology
  • Clinical Special Interests: Coronary artery disease, interventional cardiology
  • Research Special Interests: Coronary artery disease, interventional cardiology, antithrombotic therapy
  • Speaks English, Italian and Spanish

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Office Information

Academic Office
5th Floor, Ambulatory Care Center
655 West 8th Street, C35
Jacksonville, FL 32209
(904) 244-2655
Administrative Manager
Erika Jackson
(904) 244-2655
GME Office
5th Floor, Ambulatory Care Center
655 West 8th Street
Jacksonville, FL 32209
Phone: (904) 244-3066
GME Program Assistant
Sandra Reisig
(904) 244-3066


Medical Degree
1997 · The Catholic University of the Sacred Heart Medical School, Rome, Italy
Internal Medicine Residency
2001 · Catholic University of the Sacred Heart, Rome, Italy
Cardiovascular Disease Fellowship
2004 · San Carlos University Hospital, Madrid, Spain
Ph.D., Cellular and Molecular Cardiology
2006 · The Catholic University of the Sacred Heart Medical School, Rome, Italy