Scott L. Silliman, M.D.

Scott L. Silliman M.D.

Professor & Medical Director, Comprehensive Stroke Program; Program Director, Vascular Neurology Fellowship

Department: Department of Neurology
Business Phone: (904) 244-9896
Business Email: scott.silliman@jax.ufl.edu

Board Certifications

  • Neurology
  • Vascular Neurology

Clinical Profile

Specialties
  • Multiple Sclerosis
  • Neurology
  • Vascular Neurology
Interests
  • Clinical Special Interests: Cerebrovascular disease; multiple sclerosis
  • Research Special Interests: Stroke therapeutics, swallowing dysfunction associated with stroke, and stroke genetics

Publications

2021
Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage.
Neurology.():-[DOI] 10.1212/WNL.0000000000012227.[PMID] 34031201.
2020
Exercise-based swallowing intervention (McNeill Dysphagia Therapy) with adjunctive NMES to treat dysphagia post-stroke: A double-blind placebo-controlled trial.
Journal of oral rehabilitation.47(4):501-510[DOI] 10.1111/joor.12928.[PMID] 31880338.
2019
Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.
JAMA neurology.76(4):480-491[DOI] 10.1001/jamaneurol.2018.4519.[PMID] 30726504.
2019
Genome-wide association study of cerebral small vessel disease reveals established and novel loci.
Brain : a journal of neurology.142(10):3176-3189[DOI] 10.1093/brain/awz233.[PMID] 31430377.
2018
17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage.
Stroke.49(7):1618-1625[DOI] 10.1161/STROKEAHA.117.020091.[PMID] 29915124.
2018
Analysis of shared heritability in common disorders of the brain.
Science (New York, N.Y.).360(6395):-[DOI] 10.1126/science.aap8757.[PMID] 29930110.
2018
Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
Neurology-Genetics.4(6):e293-[DOI] 10.1212/NXG.0000000000000293.[PMID] .
2018
Diagnosis and Management of Acute Ischemic Stroke.
Mayo Clinic proceedings.93(4):523-538[DOI] 10.1016/j.mayocp.2018.02.013.[PMID] 29622098.
2017
Multiplanar computed tomography reconstruction to aid in recognition of the middle cerebral artery "Dot" sign: The sagittal string sign.
SAGE open medical case reports.5():2050313X17748864-[DOI] 10.1177/2050313X17748864.[PMID] 29318017.
2016
Bacterial Endocarditis and Cerebrovascular Disease.
Current neurology and neuroscience reports.16(12):104-[DOI] .[PMID] 27815693.
2016
Clinical Variables Associated with Hydration Status in Acute Ischemic Stroke Patients with Dysphagia.
Dysphagia.31(1):60-5[DOI] 10.1007/s00455-015-9658-6.[PMID] 26497649.
2016
Genetic variants in CETP increase risk of intracerebral hemorrhage.
Annals of neurology.80(5):730-740[DOI] 10.1002/ana.24780.[PMID] 27717122.
2015
Common Variation in Col4A1/Col4A2 Is Associated With Sporadic Cerebral Small Vessel Disease
Neurology.84(9):918-926[DOI] 10.1212/WNL.0000000000001309.[PMID] 25653287.
2015
Rare Coding Variation and Risk of Intracerebral Hemorrhage.
Stroke.46(8):2299-301[DOI] 10.1161/STROKEAHA.115.009838.[PMID] 26111891.
2014
APOE ε variants increase risk of warfarin-related intracerebral hemorrhage.
Neurology.83(13):1139-46[DOI] 10.1212/WNL.0000000000000816.[PMID] 25150286.
2014
Assessing the impact of health literacy on education retention of stroke patients.
Preventing chronic disease.11():E55-[DOI] 10.5888/pcd11.130259.[PMID] 24721215.
2014
Clinical Factors Impacting Dehydration in Acute Stroke
International Journal of Stroke.9(3, SI):76-77[DOI] .[PMID] .
2014
Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.
American journal of human genetics.94(4):511-21[DOI] 10.1016/j.ajhg.2014.02.012.[PMID] 24656865.
2013
Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.
Stroke.44(2):321-6[DOI] 10.1161/STROKEAHA.112.675181.[PMID] 23321443.
2013
Characteristics and outcomes of cocaine-related spontaneous intracerebral hemorrhages.
ISRN neurology.2013():124390-[DOI] 10.1155/2013/124390.[PMID] 23533805.
2013
Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage.
Stroke.44(3):612-9[DOI] 10.1161/STROKEAHA.112.672089.[PMID] 23362085.
2013
Dysphagia, nutrition, and hydration in ischemic stroke patients at admission and discharge from acute care.
Dysphagia.28(1):69-76[DOI] 10.1007/s00455-012-9414-0.[PMID] 22684924.
2013
Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage.
Stroke.44(6):1578-83[DOI] 10.1161/STROKEAHA.111.000089.[PMID] 23559261.
2013
Novel insights into the genetics of intracerebral hemorrhage.
Stroke.44(6 Suppl 1):S137-[DOI] 10.1161/STROKEAHA.113.001912.[PMID] 23709713.
2012
Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.
Stroke.43(11):2877-83[DOI] 10.1161/STROKEAHA.112.659755.[PMID] 22933587.
2012
Cogan syndrome: an analysis of reported neurological manifestations.
The neurologist.18(2):55-63[DOI] 10.1097/NRL.0b013e31823fa3a0.[PMID] 22367829.
2012
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
Neurology.78(5):334-41[DOI] 10.1212/WNL.0b013e3182452b40.[PMID] 22262751.
2011
APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study.
The Lancet. Neurology.10(8):702-9[DOI] 10.1016/S1474-4422(11)70148-X.[PMID] 21741316.
2011
Apoe Genotype Predicts Hematoma Volume and Expansion in Intracerebral Hemorrhage
.42():E102-[DOI] .[PMID] .
2011
Boosting enrolment in clinical trials: validation of a regional network model.
Clinical trials (London, England).8(5):645-53[DOI] 10.1177/1740774511414925.[PMID] 21824978.
2011
Genome Wide Association Study of Intracerebral Hemorrhage
.42():E218-E219[DOI] .[PMID] .
2011
Local Hospital Networks for Clinical Trials in Stroke
.42():E158-E159[DOI] .[PMID] .
2011
Variants At Apoe Influence Risk of Deep and Lobar Intracerebral Hemorrhage
.42():E185-[DOI] .[PMID] .
2010
Analysis of a physician tool for evaluating dysphagia on an inpatient stroke unit: the modified Mann Assessment of Swallowing Ability.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.19(1):49-57[DOI] 10.1016/j.jstrokecerebrovasdis.2009.03.007.[PMID] 20123227.
2010
Phenotypic Characteristics By Consent Status: Comparison of Self-Consent, Proxy-Consent, and Waiver of Consent in the Genetics of Cerebral Hemorrhage in Anticoagulation (Gocha) Study
.41():E337-E338[DOI] .[PMID] .
2010
Variants at APOE influence risk of deep and lobar intracerebral hemorrhage.
Annals of neurology.68(6):934-43[DOI] 10.1002/ana.22134.[PMID] 21061402.
2009
CADASIL disease, an inherited slowly progressive vascular dementia: case report with radiologic and electron microscopic findings.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.18(6):491-3[DOI] 10.1016/j.jstrokecerebrovasdis.2009.02.004.[PMID] 19900654.
2009
Exploiting common genetic variation to make anticoagulation safer.
Stroke.40(3 Suppl):S64-6[DOI] 10.1161/STROKEAHA.108.533190.[PMID] 19150865.
2008
A systematic review of outcomes in patients with staged carotid artery stenting and coronary artery bypass graft surgery.
Stroke.39(2):361-5[DOI] 10.1161/STROKEAHA.107.495010.[PMID] 18174484.
2008
Hypertriglyceridemia and ischemic stroke.
European neurology.60(6):269-78[DOI] 10.1159/000157880.[PMID] 18824854.
2008
Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent.
Stroke.39(3):831-7[DOI] 10.1161/STROKEAHA.107.494518.[PMID] 18258838.
2008
Long-Term Behavioral Symptoms in Ischemic Stroke Survivors
.39():619-[DOI] .[PMID] .
2008
Long-Term Cognitive Function in Survivors of First-Ever Ischemic Stroke
.39():707-[DOI] .[PMID] .
2008
Proband race/ethnicity affects pedigree completion rate in a genetic study of ischemic stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.17(5):299-302[DOI] 10.1016/j.jstrokecerebrovasdis.2008.02.011.[PMID] 18755410.
2008
Screening of Long-Term Functional Outcomes in Survivors of First-Ever Ischemic Stroke
.39():696-[DOI] .[PMID] .
2008
Structural genomic variation in ischemic stroke.
Neurogenetics.9(2):101-8[DOI] 10.1007/s10048-008-0119-3.[PMID] 18288507.
2007
A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.
The Lancet. Neurology.6(5):414-20[DOI] .[PMID] 17434096.
2007
Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.16(5):187-93[DOI] .[PMID] 17845914.
2007
Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.16(1):34-9[DOI] .[PMID] 17689390.
2006
Dysphagia and nutritional status at the time of hospital admission for ischemic stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.15(4):164-71[DOI] .[PMID] 17904070.
2006
Family history of stroke and severity of neurologic deficit after stroke.
Neurology.67(8):1396-402[DOI] .[PMID] 17060565.
2006
Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.15(6):266-72[DOI] .[PMID] 17904086.
2003
Simultaneous bilateral hypertensive putaminal hemorrhages.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.12(1):44-6[DOI] .[PMID] 17903903.
2003
Spouses and unrelated friends of probands as controls for stroke genetics studies.
Neuroepidemiology.22(4):239-44[DOI] .[PMID] 12792144.
2003
The Ischemic Stroke Genetics Study (ISGS) Protocol.
BMC neurology.3():4-[DOI] .[PMID] 12848902.
2003
Use of a field-to-stroke center helicopter transport program to extend thrombolytic therapy to rural residents.
Stroke.34(3):729-33[DOI] .[PMID] 12624299.
2002
Mendelian and mitochondrial disorders associated with stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.11(5):252-64[DOI] .[PMID] 17903883.
2001
Images in clinical medicine. Hemorrhagic transformation of a cerebral infarct.
The New England journal of medicine.345(15):1105-[DOI] .[PMID] 11596590.
1999
Vascular risk factors in cocaine users with stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.8(4):254-8[DOI] .[PMID] 17895173.
1995
The Warfarin-Aspirin Symptomatic Intracranial Disease Study.
Neurology.45(8):1488-93[DOI] .[PMID] 7644046.

Office Information

Academic Office
9th Floor, Tower I
580 West 8th Street, T17
Jacksonville, FL 32209
(904) 244-9831
scott.silliman@jax.ufl.edu
Administrative Manager
Sarah Conway
(904) 244-9896
SarahE.conway@jax.ufl.edu
GME Office
9th Floor, Tower I
580 West 8th Street, T17
Jacksonville, FL 32209
Phone: (904) 244-9934
Fax: (904) 244-9481
scott.silliman@jax.ufl.edu
GME Program Assistant
Shadina Williams
(904) 244-9822
Shadina.Williams@jax.ufl.edu

Education

Medical Degree
1988 · Albany Medical College, Albany, NY, USA
Neurology Residency
1992 · Albert Einstein College of Medicine, Bronx, NY, USA
Vascular Neurology Fellowship
1993 · Spaulding Rehabilitation Hospital New England Medical Center, Boston, MA, USA

Multimedia