Jose E. Irazuzta, M.D.

Jose E. Irazuzta M.D.

Professor

Department: Department of Pediatrics
Business Phone: (904) 202-8758
Business Email: Jose.irazuzta@jax.ufl.edu

Board Certifications

  • Pediatrics
  • Pediatric Critical Care Medicine

Clinical Profile

Specialties
  • Pediatric Critical Care Medicine
Interests
  • Clinical Special Interests: Neurointensive care; brain injury
  • Research Special Interests: Sepsis; acute respiratory distress syndrome

Publications

2024
Safety of Extended Propofol Infusions in Critically Ill Pediatric Patients.
Cureus.16(5):e59948-[DOI] 10.7759/cureus.59948.[PMID] 38854299.
2023
Incidence of Air Leak Syndrome in Pediatric Patients With SARS-COV-2 Pneumonia and Respiratory Failure: A Single-Center Retrospective Study.
Cureus.15(8):e43329-[DOI] 10.7759/cureus.43329.[PMID] 37700955.
2023
Multicentric validation of a prognostic tool for predicting brain death following out-of-hospital cardiac arrest in children.
Resuscitation.185():109727-[DOI] 10.1016/j.resuscitation.2023.109727.[PMID] 36764571.
2017
American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.
Critical care medicine.45(6):1061-1093[DOI] 10.1097/CCM.0000000000002425.[PMID] 28509730.
2017
Magnesium sulfate infusion for acute asthma in the emergency department.
Jornal de pediatria.93 Suppl 1():19-25[DOI] 10.1016/j.jped.2017.06.002.[PMID] 28754601.
2017
The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.18(9):884-890[DOI] 10.1097/PCC.0000000000001259.[PMID] 28723883.
2016
Bedside Optic Nerve Sheath Diameter Assessment in the Identification of Increased Intracranial Pressure in Suspected Idiopathic Intracranial Hypertension.
Pediatric neurology.54():35-8[DOI] 10.1016/j.pediatrneurol.2015.08.009.[PMID] 26481981.
2016
Comparison of Two High-Dose Magnesium Infusion Regimens in the Treatment of Status Asthmaticus.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG.21(3):233-8[DOI] 10.5863/1551-6776-21.3.233.[PMID] 27453701.
2013
High-dose magnesium sulfate infusion protocol for status asthmaticus: a safety and pharmacokinetics cohort study.
Intensive care medicine.39(1):117-22[DOI] 10.1007/s00134-012-2734-6.[PMID] 23129148.
2012
Feasibility of short-term infusion of magnesium sulfate in pediatric patients with status asthmaticus.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG.17(2):150-4[DOI] 10.5863/1551-6776-17.2.150.[PMID] 23118666.
2012
Primary amebic meningoencephalitis: a case report and literature review.
Pediatric emergency care.28(3):272-6[DOI] 10.1097/PEC.0b013e3182495589.[PMID] 22391923.
2011
Learner's evaluation in paediatric intensive care unit.
Emergency medicine journal : EMJ.28(9):758-60[DOI] 10.1136/emj.2009.088294.[PMID] 20798083.
2011
Postmortem studies in the contemporary pediatric intensive care unit.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.12(6):617-21[DOI] 10.1097/PCC.0b013e3182071266.[PMID] 21242857.
2010
Hyperacute therapies for childhood stroke: a case report and review of the literature.
Neurology research international.2010():497326-[DOI] 10.1155/2010/497326.[PMID] 21152213.
2009
Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine.
Critical care medicine.37(2):666-88[DOI] 10.1097/CCM.0b013e31819323c6.[PMID] 19325359.
2009
Fulminant pertussis: a multi-center study with new insights into the clinico-pathological mechanisms.
Pediatric pulmonology.44(10):970-80[DOI] 10.1002/ppul.21082.[PMID] 19725100.
2008
Caspases inhibition decreases neurological sequelae in meningitis.
Critical care medicine.36(5):1603-6[DOI] 10.1097/CCM.0b013e318170ab08.[PMID] 18434888.
2007
Pharmacologic support of infants and children in septic shock.
Jornal de pediatria.83(2 Suppl):S36-45[DOI] .[PMID] 17530137.
2005
Dexamethasone decreases neurological sequelae and caspase activity.
Intensive care medicine.31(1):146-50[DOI] .[PMID] 15502933.
2004
Technology: mechanical ventilation strategy versus tactics.
Jornal de pediatria.80(3):169-70[DOI] .[PMID] 15192757.
2002
Modulation of nuclear factor-kappaB activation and decreased markers of neurological injury associated with hypothermic therapy in experimental bacterial meningitis.
Critical care medicine.30(11):2553-9[DOI] .[PMID] 12441769.
2001
Amrinone in pediatric refractory septic shock: An open-label pharmacodynamic study.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.2(1):24-28[DOI] .[PMID] 12797884.
2001
Hypothermia attenuates beta1 integrin expression on extravasated neutrophils in an animal model of meningitis.
Inflammation.25(3):137-44[DOI] .[PMID] 11403204.
2001
La Crosse encephalitis in children.
The New England journal of medicine.344(11):801-7[DOI] .[PMID] 11248155.
2001
Serum cleaved Tau protein and neurobehavioral battery of tests as markers of brain injury in experimental bacterial meningitis.
Brain research.913(1):95-105[DOI] .[PMID] 11532253.
2000
Evaluating the frequency rate of hypomagnesemia in critically ill pediatric patients by using multiple regression analysis and a computer-based neural network.
Critical care medicine.28(10):3534-9[DOI] .[PMID] 11057813.
2000
Hypothermia as an adjunctive treatment for severe bacterial meningitis.
Brain research.881(1):88-97[DOI] .[PMID] 11033098.
2000
Integrin expression on neutrophils in a rabbit model of Group B Streptococcal meningitis.
Inflammation.24(2):157-73[DOI] .[PMID] 10718117.
2000
Mercaptoethylguanidine attenuates inflammation in bacterial meningitis in rabbits.
Life sciences.67(4):365-72[DOI] .[PMID] 11003046.
1999
Hypothermia decreases excitatory neurotransmitter release in bacterial meningitis in rabbits.
Brain research.847(1):143-8[DOI] .[PMID] 10564748.
1999
Topical nitroglycerin and pain in purpura fulminans.
The Journal of pediatrics.134(5):639-41[DOI] .[PMID] 10228302.
1998
Compared contralateral application of topical nitroglycerin on purpura fulminans.
The West Virginia medical journal.94(1):29-30[DOI] .[PMID] 9505568.
1998
Decrease in costs for management of lower airway disease in the pediatric intensive care unit.
Southern medical journal.91(7):655-9[DOI] .[PMID] 9671837.
1998
Utilization of diagnostic resources for meningoencephalitis in the pediatric ICU.
The West Virginia medical journal.94(3):146-9[DOI] .[PMID] 9641073.
1997
Outcome and cost of child abuse.
Child abuse & neglect.21(8):751-7[DOI] .[PMID] 9280380.
1997
Simple method of multipurpose airway access through percutaneous tracheostomy in rabbits (Oryctolagus cuniculus).
Laboratory animal science.47(4):411-3[DOI] .[PMID] 9306316.
1996
Intratracheal administration of fentanyl: pharmacokinetics and local tissue effects.
Intensive care medicine.22(2):129-33[DOI] .[PMID] 8857120.
1995
Selective pulmonary suctioning using a tip deflecting wire in mechanically ventilated patients.
Critical care medicine.23(2):410-1[DOI] .[PMID] 7867367.
1993
Effects of fentanyl administration on respiratory system compliance in infants.
Critical care medicine.21(7):1001-4[DOI] .[PMID] 8319456.
1993
Monitoring in pediatric intensive care.
Indian journal of pediatrics.60(1):55-65[DOI] .[PMID] 8244487.

Office Information

Academic Office
Wolfson Children's Hospital
800 Prudential Drive, 3rd Floor
Jacksonville, FL 32207
(904) 202-8758
Jose.irazuzta@jax.ufl.edu
Administrative Manager
Amanda Thornton
(904) 202-8758
amanda.thornton@jax.ufl.edu

Education

Medical Degree
1980 · Universidad Nacional de Cordoba, Cordoba, Argentina
Pediatrics Residency
1987 · University of Louisville Kosair Children's Hospital, Louisville, KY, USA
Pediatric Critical Care Medicine Fellowship
1990 · Boston Children's Hospital, Boston, MA, USA