James W. Dennis, M.D.

James W. Dennis M.D.

Professor & Associate Chair, Educational and Faculty Affairs; Chief, Division of Vascular Surgery

Department: Department of Surgery
Business Phone: (904) 244-7418
Business Email: james.dennis@jax.ufl.edu

Board Certifications

  • Surgery
  • Vascular Surgery
  • Surgical Critical Care

Clinical Profile

Specialties
  • Vascular Surgery
Interests
  • Clinical Special Interests: Abdominal aortic aneurysms, lower extremity ischemia and carotid artery disease

Publications

2019
Identification of unique characteristics and the management of blunt traumatic aortic injuries occurring at unusual locations in the descending thoracic aorta.
Journal of vascular surgery.69(1):40-46[DOI] 10.1016/j.jvs.2018.06.208.[PMID] 30579457.
2018
Gallbladder Rupture and Acute Thoracic Aortic Disruption after Blunt Trauma.
The American surgeon.84(9):e436-e438[DOI] .[PMID] 30454527.
2018
Novel application of an old technique: the use of external to internal carotid artery transposition in trauma.
Trauma surgery & acute care open.3(1):e000182-[DOI] 10.1136/tsaco-2018-000182.[PMID] 29766144.
2018
Reassessing the utility of CT angiograms in penetrating injuries to the extremities.
Surgery.163(2):419-422[DOI] 10.1016/j.surg.2017.09.019.[PMID] 29167019.
2014
The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.
Science signaling.7(313):ra17-[DOI] 10.1126/scisignal.2004785.[PMID] 24550542.
2013
Probing the hexosamine biosynthetic pathway in human tumor cells by multitargeted tandem mass spectrometry.
ACS chemical biology.8(9):2053-62[DOI] 10.1021/cb4004173.[PMID] 23875632.
2013
Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
Nature.499(7457):166-71[DOI] 10.1038/nature12308.[PMID] 23846654.
2012
A prospective randomized study comparing fibrin sealant to manual compression for the treatment of anastomotic suture-hole bleeding in expanded polytetrafluoroethylene grafts.
Journal of vascular surgery.56(1):134-41[DOI] 10.1016/j.jvs.2012.01.009.[PMID] 22633423.
2012
Diagnosis and management of evacuated casualties with cervical vascular injuries resulting from combat-related explosive blasts.
Journal of vascular surgery.55(5):1329-36; discussion 1336[DOI] 10.1016/j.jvs.2011.11.125.[PMID] 22325667.
2012
Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells.
The Journal of biological chemistry.287(39):32940-52[DOI] .[PMID] 22846995.
2012
Imaging stem cell differentiation for cell-based tissue repair.
Methods in enzymology.506():247-63[DOI] 10.1016/B978-0-12-391856-7.00037-8.[PMID] 22341228.
2012
Suppression of cancer progression by MGAT1 shRNA knockdown.
PloS one.7(9):e43721-[DOI] 10.1371/journal.pone.0043721.[PMID] 22957033.
2012
The eggshell in the C. elegans oocyte-to-embryo transition.
Genesis (New York, N.Y. : 2000).50(4):333-49[DOI] 10.1002/dvg.20823.[PMID] 22083685.
2011
Characterization and Management of Cervical Vascular Injuries Resulting From Improvised Explosive Devices (Ieds) and Rocket Propelled Grenades (Rpgs)
Journal of Vascular Surgery.53():9S-10S[DOI] .[PMID] .
2011
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Nature communications.2():334-[DOI] 10.1038/ncomms1333.[PMID] 21629267.
2011
Glycosylation, galectins and cellular signaling.
Current opinion in cell biology.23(4):383-92[DOI] 10.1016/j.ceb.2011.05.001.[PMID] 21616652.
2011
High-throughput lectin magnetic bead array-coupled tandem mass spectrometry for glycoprotein biomarker discovery.
Electrophoresis.32(24):3564-75[DOI] 10.1002/elps.201100341.[PMID] 22180208.
2010
Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia.
Leukemia.24(9):1588-98[DOI] 10.1038/leu.2010.152.[PMID] 20668475.
2010
Eggshell chitin and chitin-interacting proteins prevent polyspermy in C. elegans.
Current biology : CB.20(21):1932-7[DOI] 10.1016/j.cub.2010.09.059.[PMID] 20971008.
2010
Plk4 is required for cytokinesis and maintenance of chromosomal stability.
Proceedings of the National Academy of Sciences of the United States of America.107(15):6888-93[DOI] 10.1073/pnas.0910941107.[PMID] 20348415.
2010
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism.
Genes & development.24(24):2784-99[DOI] 10.1101/gad.1985910.[PMID] 21106670.
2009
Adaptive regulation at the cell surface by N-glycosylation.
Traffic (Copenhagen, Denmark).10(11):1569-78[DOI] 10.1111/j.1600-0854.2009.00981.x.[PMID] 19761541.
2009
Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae.
Journal of cellular and molecular medicine.13(9B):3218-25[DOI] 10.1111/j.1582-4934.2009.00732.x.[PMID] 19438805.
2009
Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane.
The Journal of cell biology.185(3):381-5[DOI] 10.1083/jcb.200811059.[PMID] 19398762.
2009
Metabolism, cell surface organization, and disease.
Cell.139(7):1229-41[DOI] 10.1016/j.cell.2009.12.008.[PMID] 20064370.
2008
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization.
Apoptosis : an international journal on programmed cell death.13(3):413-22[DOI] 10.1007/s10495-007-0175-4.[PMID] 18181020.
2008
Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice.
Genes, brain, and behavior.7(3):334-43[DOI] .[PMID] 17883406.
2008
Biological implications of SNPs in signal peptide domains of human proteins.
Proteins.70(2):394-403[DOI] .[PMID] 17680692.
2008
Genome-scale identification of UDP-GlcNAc-dependent pathways.
Proteomics.8(16):3294-302[DOI] 10.1002/pmic.200800208.[PMID] 18646010.
2008
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function.
Cancer research.68(16):6688-97[DOI] 10.1158/0008-5472.CAN-07-6833.[PMID] 18701493.
2008
N-Glycans in cancer progression.
Glycobiology.18(10):750-60[DOI] 10.1093/glycob/cwn071.[PMID] 18701722.
2007
Complex N-glycan and metabolic control in tumor cells.
Cancer research.67(20):9771-80[DOI] .[PMID] 17942907.
2007
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.
Cell.129(1):123-34[DOI] .[PMID] 17418791.
2007
Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis.
The Journal of biological chemistry.282(27):20027-35[DOI] .[PMID] 17488719.
2007
Imaging of mesenchymal stem cell transplant by bioluminescence and PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.48(12):2011-20[DOI] .[PMID] 18006616.
2007
Metabolic homeostasis and tissue renewal are dependent on beta1,6GlcNAc-branched N-glycans.
Glycobiology.17(8):828-37[DOI] .[PMID] 17483135.
2007
Mgat5 and Pten interact to regulate cell growth and polarity.
Glycobiology.17(7):767-73[DOI] .[PMID] 17400585.
2007
Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.
Nature cell biology.9(10):1131-41[DOI] .[PMID] 17891141.
2007
Plasma membrane domain organization regulates EGFR signaling in tumor cells.
The Journal of cell biology.179(2):341-56[DOI] .[PMID] 17938246.
2006
Chemical enhancers of cytokine signaling that suppress microfilament turnover and tumor cell growth.
Cancer research.66(7):3558-66[DOI] .[PMID] 16585180.
2006
Cytokine sensitivity and N-glycan processing mutations.
Methods in enzymology.417():3-11[DOI] .[PMID] 17132493.
2006
Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.
Biochimica et biophysica acta.1760(4):678-84[DOI] .[PMID] 16413118.
2006
Galectin binding to Mgat5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells.
Molecular and cellular biology.26(8):3181-93[DOI] .[PMID] 16581792.
2006
The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.
BMC biology.4():35-[DOI] .[PMID] 17042944.
2005
Dynamic changes in clinical features and cytokine/chemokine responses in SARS patients treated with interferon alfacon-1 plus corticosteroids.
Antiviral therapy.10(2):263-75[DOI] .[PMID] 15865221.
2005
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.
Nature genetics.37(8):883-8[DOI] .[PMID] 16025114.
2005
Redefining the role of arterial imaging in the management of penetrating zone 3 neck injuries.
Vascular.13(3):158-63[DOI] .[PMID] 15996373.
2005
Regulation of BMP-induced ectopic bone formation by Ahsg.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.23(3):653-62[DOI] .[PMID] 15885488.
2005
Sak/Plk4 and mitotic fidelity.
Oncogene.24(2):306-12[DOI] .[PMID] 15640847.
2005
Simple enzymatic means to neutralize DNA contamination in nucleic acid amplification.
BioTechniques.39(1):69-73[DOI] .[PMID] 16060371.
2005
The lipid composition of autophagic vacuoles regulates expression of multilamellar bodies.
Journal of cell science.118(Pt 9):1991-2003[DOI] .[PMID] 15840653.
2005
Tumor cell pseudopodial protrusions. Localized signaling domains coordinating cytoskeleton remodeling, cell adhesion, glycolysis, RNA translocation, and protein translation.
The Journal of biological chemistry.280(34):30564-73[DOI] .[PMID] 15985431.
2004
alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression.
Cancer research.64(18):6402-9[DOI] .[PMID] 15374947.
2004
N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells.
Journal of immunology (Baltimore, Md. : 1950).173(12):7200-8[DOI] .[PMID] 15585841.
2004
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.
Science (New York, N.Y.).306(5693):120-4[DOI] .[PMID] 15459394.
2003
Impaired residents: identification and intervention.
Current surgery.60(2):214-7[DOI] .[PMID] 14972299.
2003
Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study.
JAMA.290(24):3222-8[DOI] .[PMID] 14693875.
2003
STAT1 and STAT3 alpha/beta splice form activation predicts host responses in mouse hepatitis virus type 2 infection. J Med Virol 2003;69:306-312.
Journal of medical virology.71(3):474-[DOI] .[PMID] 12966557.
2003
STAT1 and STAT3 alpha/beta splice form activation predicts host responses in mouse hepatitis virus type 3 infection.
Journal of medical virology.69(3):306-12[DOI] .[PMID] 12526039.
2002
alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling.
The Journal of biological chemistry.277(22):19991-7[DOI] .[PMID] 11901155.
2002
Confirmation of the safety and accuracy of physical examination in the evaluation of knee dislocation for injury of the popliteal artery: a prospective study.
The Journal of trauma.52(2):247-51; discussion 251[DOI] .[PMID] 11834983.
2002
Extensive pneumocranium.
The Journal of trauma.52(1):188-[DOI] .[PMID] 11791076.
2002
The Caenorhabditis elegans gene, gly-2, can rescue the N-acetylglucosaminyltransferase V mutation of Lec4 cells.
The Journal of biological chemistry.277(25):22829-38[DOI] .[PMID] 11937505.
2002
The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization.
Nature structural biology.9(10):719-24[DOI] .[PMID] 12352953.
2002
UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice.
Biochimica et biophysica acta.1573(3):414-22[DOI] .[PMID] 12417426.
2001
Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer.
Annals of surgical oncology.8(9):729-40[DOI] .[PMID] 11597015.
2001
Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues.
Glycobiology.11(11):979-88[DOI] .[PMID] 11744632.
2001
Genetic defects in N-glycosylation and cellular diversity in mammals.
Current opinion in structural biology.11(5):601-7[DOI] .[PMID] 11785762.
2001
Late mitotic failure in mice lacking Sak, a polo-like kinase.
Current biology : CB.11(6):441-6[DOI] .[PMID] 11301255.
2001
Long-term follow-up of prophylactic greenfield filters in multisystem trauma patients.
The Journal of trauma.51(6):1087-90; discussion 1090[DOI] .[PMID] 11740258.
2001
Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation.
Nature.409(6821):733-9[DOI] .[PMID] 11217864.
2001
Quality control of resident operative experience: compliance with RRC criteria.
The Journal of surgical research.98(2):81-4[DOI] .[PMID] 11397122.
2000
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors.
Analytical biochemistry.280(1):137-42[DOI] .[PMID] 10805531.
2000
Biogenesis of multilamellar bodies via autophagy.
Molecular biology of the cell.11(1):255-68[DOI] .[PMID] 10637306.
2000
Continued experience with physical examination alone for evaluation and management of penetrating zone 2 neck injuries: results of 145 cases.
Journal of vascular surgery.32(3):483-9[DOI] .[PMID] 10957654.
2000
Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.
The EMBO journal.19(19):5092-104[DOI] .[PMID] 11013212.
2000
Minimal catalytic domain of N-acetylglucosaminyltransferase V.
Glycobiology.10(6):595-9[DOI] .[PMID] 10814701.
2000
Regulation of human monocyte proMMP-9 production by fetuin, an endogenous TGF-beta antagonist.
Journal of cellular physiology.185(2):174-83[DOI] .[PMID] 11025439.
2000
Sak kinase gene structure and transcriptional regulation.
Gene.241(1):65-73[DOI] .[PMID] 10607900.
2000
Suppression of tumor growth and metastasis in Mgat5-deficient mice.
Nature medicine.6(3):306-12[DOI] .[PMID] 10700233.
1999
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research.
Glycoconjugate journal.16(10):607-15[DOI] .[PMID] 10972139.
1999
Glycoprotein glycosylation and cancer progression.
Biochimica et biophysica acta.1473(1):21-34[DOI] .[PMID] 10580127.
1999
Overexpression of core 2 N-acetylglycosaminyltransferase enhances cytokine actions and induces hypertrophic myocardium in transgenic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.13(15):2329-37[DOI] .[PMID] 10593880.
1999
Protein glycosylation in development and disease.
BioEssays : news and reviews in molecular, cellular and developmental biology.21(5):412-21[DOI] .[PMID] 10376012.
1999
Regulation of osteogenesis by fetuin.
The Journal of biological chemistry.274(40):28514-20[DOI] .[PMID] 10497215.
1998
A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis.
Journal of vascular surgery.28(3):464-70; discussion 470[DOI] .[PMID] 9737456.
1998
The extent of polylactosamine glycosylation of MDCK LAMP-2 is determined by its Golgi residence time.
Glycobiology.8(9):947-53[DOI] .[PMID] 9675228.
1998
The Internet and education in surgery.
The American surgeon.64(9):877-80[DOI] .[PMID] 9731818.
1998
Validation of nonoperative management of occult vascular injuries and accuracy of physical examination alone in penetrating extremity trauma: 5- to 10-year follow-up.
The Journal of trauma.44(2):243-52; discussion 242[DOI] .[PMID] 9498494.
1997
Modification of CD43 and other lymphocyte O-glycoproteins by core 2 N-acetylglucosaminyltransferase.
Glycobiology.7(1):129-36[DOI] .[PMID] 9061371.
1997
Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research.3(7):1077-86[DOI] .[PMID] 9815786.
1996
Changing patterns of arterial injuries associated with fractures and dislocations.
Journal of the American College of Surgeons.183(4):377-83[DOI] .[PMID] 8843267.
1996
Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation.
Molecular and cellular biology.16(9):4665-72[DOI] .[PMID] 8756623.
1996
Fetuin/alpha2-HS glycoprotein is a transforming growth factor-beta type II receptor mimic and cytokine antagonist.
The Journal of biological chemistry.271(22):12755-61[DOI] .[PMID] 8662721.
1995
Complex asparagine-linked oligosaccharides in Mgat1-null embryos.
Glycobiology.5(5):535-43[DOI] .[PMID] 8563140.
1995
GlcNAc-transferase V and core 2 GlcNAc-transferase expression in the developing mouse embryo.
Glycobiology.5(8):797-806[DOI] .[PMID] 8720078.
1995
Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue.
The Journal of clinical investigation.96(4):1759-67[DOI] .[PMID] 7560067.
1995
Inhibitors of carbohydrate processing: A new class of anticancer agents.
Clinical cancer research : an official journal of the American Association for Cancer Research.1(9):935-44[DOI] .[PMID] 9816064.
1995
Prophylactic Greenfield filter placement in selected high-risk trauma patients.
Journal of vascular surgery.22(3):231-5; discussion 235[DOI] .[PMID] 7674465.
1995
Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V.
The Journal of cell biology.130(2):383-92[DOI] .[PMID] 7615638.
1995
Regarding "Adverse outcome of nonoperative management of intimal injuries caused by penetrating trauma".
Journal of vascular surgery.22(1):119-20[DOI] .[PMID] 7602702.
1994
A phase I study of swainsonine in patients with advanced malignancies.
Cancer research.54(6):1450-7[DOI] .[PMID] 8137247.
1994
Branching N-linked oligosaccharides in breast cancer.
Advances in experimental medicine and biology.353():95-104[DOI] .[PMID] 7985545.
1994
Measuring swainsonine in serum of cancer patients: phase I clinical trial.
Clinical chemistry.40(3):426-30[DOI] .[PMID] 8131279.
1994
Physical examination alone is safe and accurate for evaluation of vascular injuries in penetrating Zone II neck trauma.
Journal of the American College of Surgeons.179(6):657-62[DOI] .[PMID] 7952477.
1994
Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America.91(14):6388-92[DOI] .[PMID] 8022793.
1994
Sialylation and malignant potential in tumour cell glycosylation mutants.
Glycobiology.4(5):665-74[DOI] .[PMID] 7881181.
1993
Antisense and sense cDNA expression cloning using autonomously replicating vectors and toxic lectin selection.
Biochemical and biophysical research communications.195(2):814-22[DOI] .[PMID] 8373417.
1993
Branching beta 1-6N-acetylglucosaminetransferases and polylactosamine expression in mouse F9 teratocarcinoma cells and differentiated counterparts.
The Journal of biological chemistry.268(2):1242-51[DOI] .[PMID] 8419327.
1993
Carbonoyloxy analogs of the anti-metastatic drug swainsonine. Activation in tumor cells by esterases.
Biochemical pharmacology.46(8):1459-66[DOI] .[PMID] 8240396.
1993
Core 2 GlcNAc-transferase and polylactosamine expression in O-glycans.
Glycobiology.3(2):91-3[DOI] .[PMID] 8490245.
1993
Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich syndrome (WAS).
Clinical and experimental immunology.91(1):43-9[DOI] .[PMID] 8380367.
1993
Efficacy of deep venous thrombosis prophylaxis in trauma patients and identification of high-risk groups.
The Journal of trauma.35(1):132-8; discussion 138[DOI] .[PMID] 8331703.
1993
Inhibition of N-linked oligosaccharide processing in tumor cells is associated with enhanced tissue inhibitor of metalloproteinases (TIMP) gene expression.
International journal of cancer.53(4):634-9[DOI] .[PMID] 8436437.
1993
Reassessing the role of arteriograms in the management of posterior knee dislocations.
The Journal of trauma.35(5):692-5; discussion 695[DOI] .[PMID] 8230331.
1993
Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells.
The Journal of biological chemistry.268(8):5409-16[DOI] .[PMID] 8383671.
1992
A coupled assay for UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1,6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc).
Analytical biochemistry.206(2):262-6[DOI] .[PMID] 1443596.
1992
Are arteriograms necessary in penetrating zone II neck injuries?
Journal of vascular surgery.16(3):397-400; discussion 400[DOI] .[PMID] 1522642.
1992
Conservative treatment of penetrating vascular wounds: reply.
Surgery.111(1):119-20[DOI] .[PMID] 1728069.
1992
Superiority of end-diastolic volume and ejection fraction measurements over wedge pressures in evaluating cardiac function during aortic reconstruction.
Journal of vascular surgery.16(3):372-7[DOI] .[PMID] 1522639.
1991
Aberrant O-linked oligosaccharide biosynthesis in lymphocytes and platelets from patients with the Wiskott-Aldrich syndrome.
The Journal of biological chemistry.266(10):6280-90[DOI] .[PMID] 2007580.
1991
Autocrine and paracrine regulation of tissue inhibitor of metalloproteinases, transin, and urokinase gene expression in metastatic and nonmetastatic mammary carcinoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.2(7):335-41[DOI] .[PMID] 1782152.
1991
Beta 1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia.
Cancer research.51(2):718-23[DOI] .[PMID] 1985789.
1991
Characterization of O-linked oligosaccharide biosynthesis in cultured cells using paranitrophenyl alpha-D-GalNAc as an acceptor.
Glycobiology.1(4):425-33[DOI] .[PMID] 1820202.
1991
Increased UDP-GlcNAc:Gal beta 1-3GaLNAc-R (GlcNAc to GaLNAc) beta-1, 6-N-acetylglucosaminyltransferase activity in metastatic murine tumor cell lines. Control of polylactosamine synthesis.
The Journal of biological chemistry.266(3):1772-82[DOI] .[PMID] 1824844.
1991
N-linked oligosaccharide processing and autocrine stimulation of tumor cell proliferation.
Experimental cell research.192(2):612-21[DOI] .[PMID] 1899075.
1991
N-linked oligosaccharide processing and tumor cell biology.
Seminars in cancer biology.2(6):411-20[DOI] .[PMID] 1810469.
1991
Nonoperative observation of clinically occult arterial injuries: a prospective evaluation.
Surgery.109(1):85-96[DOI] .[PMID] 1984640.
1991
Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells.
Nucleic acids research.19(1):85-92[DOI] .[PMID] 2011514.
1991
The reliability of physical examination in the evaluation of penetrating extremity trauma for vascular injury: results at one year.
The Journal of trauma.31(4):502-11[DOI] .[PMID] 2020036.
1991
Tn antigen and UDP-Gal:GalNAc alpha-R beta 1-3Galactosyltransferase expression in human breast carcinoma.
Cancer biochemistry biophysics.12(3):185-98[DOI] .[PMID] 1844911.
1990
Basement membrane invasion by first trimester human trophoblast: requirement for branched complex-type Asn-linked oligosaccharides.
Clinical & experimental metastasis.8(4):305-17[DOI] .[PMID] 2112436.
1990
Growth inhibition of human melanoma tumor xenografts in athymic nude mice by swainsonine.
Cancer research.50(6):1867-72[DOI] .[PMID] 2106389.
1990
New perspectives on the management of penetrating trauma in proximity to major limb arteries.
Journal of vascular surgery.11(1):84-92; discussion 92[DOI] .[PMID] 2296106.
1990
Tumor cell surface beta 1-4-linked galactose binds to lectin(s) on microvascular endothelial cells and contributes to organ colonization.
The Journal of cell biology.111(2):773-81[DOI] .[PMID] 2116422.
1989
A reassessment of the role of arteriography in penetrating proximity extremity trauma: a prospective study.
The Journal of trauma.29(8):1041-50; discussion 1050[DOI] .[PMID] 2503620.
1989
Altered expression of leucocyte sialoglycoprotein in Wiskott-Aldrich syndrome is associated with a specific defect in O-glycosylation.
Biochemistry and cell biology = Biochimie et biologie cellulaire.67(9):503-9[DOI] .[PMID] 2803729.
1989
Asparagine-linked oligosaccharides associated with metastatic cancer.
Cancer cells (Cold Spring Harbor, N.Y. : 1989).1(3):87-92[DOI] .[PMID] 2701653.
1989
Asparagine-linked oligosaccharides in malignant tumour growth.
Biochemical Society transactions.17(1):29-31[DOI] .[PMID] 2714513.
1989
Evidence that beta 1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes.
International journal of cancer.44(4):685-90[DOI] .[PMID] 2507455.
1989
Inhibition of human HT29 colon carcinoma growth in vitro and in vivo by swainsonine and human interferon-alpha 2.
Journal of the National Cancer Institute.81(13):1028-33[DOI] .[PMID] 2499693.
1989
Macrophage/biomaterial interactions: the stimulation of endothelialization.
Journal of vascular surgery.9(4):588-93[DOI] .[PMID] 2523491.
1989
Molecular characterization of P2B/LAMP-1, a major protein target of a metastasis-associated oligosaccharide structure.
Cancer research.49(21):6077-84[DOI] .[PMID] 2676155.
1989
Oncodevelopmental expression of--GlcNAc beta 1-6Man alpha 1-6Man beta 1--branched asparagine-linked oligosaccharides in murine tissues and human breast carcinomas.
Cancer research.49(4):945-50[DOI] .[PMID] 2521456.
1989
Oncogenes conferring metastatic potential induce increased branching of Asn-linked oligosaccharides in rat2 fibroblasts.
Oncogene.4(7):853-60[DOI] .[PMID] 2666906.
1988
Asn-linked oligosaccharide processing and malignant potential.
Cancer surveys.7(4):573-95[DOI] .[PMID] 3072067.
1988
Glycosylation-dependent collagen-binding activities of two membrane glycoproteins in MDAY-D2 tumor cells.
Cancer research.48(17):4743-8[DOI] .[PMID] 3409215.
1988
Isolation and characterization of spontaneous wheat germ agglutinin-resistant human melanoma mutants displaying remarkably different metastatic profiles in nude mice.
Cancer research.48(3):665-70[DOI] .[PMID] 3335029.
1988
Polyglactin 910/polydioxanone bicomponent totally resorbable vascular prostheses.
Journal of vascular surgery.7(5):697-705[DOI] .[PMID] 3130496.
1988
Secondary vascular procedures with polytetrafluoroethylene grafts for lower extremity ischemia in a male veteran population.
Journal of vascular surgery.8(2):137-42[DOI] .[PMID] 3398170.
1987
Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.
Science (New York, N.Y.).236(4801):582-5[DOI] .[PMID] 2953071.
1987
Biomaterial pretreatment with ECGF to augment endothelial cell proliferation.
Journal of vascular surgery.5(2):393-9[DOI] .[PMID] 2950245.
1987
Compound polyglactin 910/polypropylene small vessel prostheses.
Journal of vascular surgery.5(4):572-83[DOI] .[PMID] 3550160.
1987
Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2.
Cancer research.47(1):150-9[DOI] .[PMID] 3791202.
1987
Tumor cell surface carbohydrate and the metastatic phenotype.
Cancer metastasis reviews.5(3):185-204[DOI] .[PMID] 3549035.
1986
Anastomotic pseudoaneurysms. A continuing late complication of vascular reconstructive procedures.
Archives of surgery (Chicago, Ill. : 1960).121(3):314-7[DOI] .[PMID] 3947229.
1986
Different metastatic phenotypes in two genetic classes of wheat germ agglutinin-resistant tumor cell mutants.
Cancer research.46(9):4594-600[DOI] .[PMID] 3755374.
1986
Effects of swainsonine and polyinosinic:polycytidylic acid on murine tumor cell growth and metastasis.
Cancer research.46(10):5131-6[DOI] .[PMID] 3093060.
1986
The relationship between neointimal fibrous hyperplasia and distal anastomotic angles in vein bypass grafts.
Current surgery.43(3):202-5[DOI] .[PMID] 3731832.
1985
Recognition of asparagine-linked oligosaccharides on murine tumor cells by natural killer cells.
Cancer research.45(12 Pt 1):6034-40[DOI] .[PMID] 4063962.
1984
Asparagine-linked oligosaccharides in murine tumor cells: comparison of a WGA-resistant (WGAr) nonmetastatic mutant and a related WGA-sensitive (WGAs) metastatic line.
The Journal of cell biology.99(3):1034-44[DOI] .[PMID] 6547960.
1984
Carcinoma masquerading as a pancreatic pseudocyst on ultrasound.
The American surgeon.50(6):334-9[DOI] .[PMID] 6203450.
1984
Identification of asparagine-linked oligosaccharides involved in tumor cell adhesion to laminin and type IV collagen.
The Journal of cell biology.99(4 Pt 1):1416-23[DOI] .[PMID] 6237114.
1983
Genotypic and phenotypic evolution of a murine tumor during its progression in vivo toward metastasis.
Journal of the National Cancer Institute.71(1):183-91[DOI] .[PMID] 6575202.
1983
Phenotypic and genotypic differences between high- and low-metastatic related tumor lines and the problem of tumor progression and variant generation.
Symposium on Fundamental Cancer Research.36():81-99[DOI] .[PMID] 6332358.
1983
Relevance of spontaneous in vivo tumor-host cell fusion to tumor progression and metastasis evaluated using a series of lectin-resistant mutant tumor sublines.
Symposium on Fundamental Cancer Research.36():47-79[DOI] .[PMID] 6382520.
1983
Spontaneous fusion in vivo between normal host and tumor cells: possible contribution to tumor progression and metastasis studied with a lectin-resistant mutant tumor.
Molecular and cellular biology.3(4):523-38[DOI] .[PMID] 6687920.
1981
Characterization of a deficiency in fucose metabolism in lectin-resistant variants of a murine tumor showing altered tumorigenic and metastatic capacities in vivo.
Cancer research.41(1):98-104[DOI] .[PMID] 7448779.
1981
Demonstration of a correlation between tumor cell H-2 antigen content, immunogenicity, and tumorigenicity using lectin-resistant tumor variants.
Cancer research.41(10):4010-9[DOI] .[PMID] 6974593.

Office Information

Academic Office
3rd Floor, Faculty Clinic
653 West 8th Street
Jacksonville, FL 32209
(904) 244-7418
james.dennis@jax.ufl.edu
Senior Medical Secretary
Jessica Norris
(904) 244-7418
jessica.norris@jax.ufl.edu

Education

Medical Degree
1980 · Indiana University School of Medicine, Indianapolis, IN, USA
Surgery Residency
1985 · Loyola University Medical Center, Maywood, IL, USA
Vascular Surgery Fellowship
1987 · Loyola University Medical Center, Maywood, IL, USA

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