Publications

2023

Velo-epiglottic Adhesion: An Unusual Finding in a Mallampati Zero Airway.

Anesthesiology.139(5):664-[DOI] 10.1097/ALN.0000000000004643.[PMID] 37552086.

PubMed·Publisher's Site

2022

Brachial Plexus Block for Removal of Retained Radial Artery Sheath.

Cureus.14(12):e33068-[DOI] 10.7759/cureus.33068.[PMID] 36726880.

PubMed·Publisher's Site

2022

Complications From Operator Modification of the Esophageal Temperature Probe.

Cureus.14(10):e30388-[DOI] 10.7759/cureus.30388.[PMID] 36407202.

PubMed·Publisher's Site

2017

Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells.

Biochimica et biophysica acta. Molecular basis of disease.1863(7):1709-1717[DOI] 10.1016/j.bbadis.2017.05.011.[PMID] 28501567.

15 citations·PubMed·Publisher's Site

2017

Effects of psychological eating behaviour domains on the association between socio-economic status and BMI.

Public health nutrition.20(15):2706-2712[DOI] 10.1017/S1368980017001653.[PMID] 28735590.

12 citations·PubMed·Publisher's Site

2017

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.

Molecular metabolism.6(1):86-100[DOI] 10.1016/j.molmet.2016.11.003.[PMID] 28123940.

70 citations·PubMed·Publisher's Site

2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

PLoS medicine.14(9):e1002383-[DOI] 10.1371/journal.pmed.1002383.[PMID] 28898252.

268 citations·PubMed·Publisher's Site

2017

IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits.

Scientific reports.7(1):12369-[DOI] 10.1038/s41598-017-12393-5.[PMID] 28959056.

12 citations·PubMed·Publisher's Site

2016

Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection.

Liver international : official journal of the International Association for the Study of the Liver.36(9):1267-74[DOI] 10.1111/liv.13094.[PMID] 26880346.

27 citations·PubMed·Publisher's Site

2016

Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations.

International journal of obesity (2005).40(2):260-5[DOI] 10.1038/ijo.2015.157.[PMID] 26285604.

25 citations·PubMed·Publisher's Site

2016

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots.

Obesity (Silver Spring, Md.).24(10):2092-100[DOI] 10.1002/oby.21571.[PMID] 27515773.

46 citations·PubMed·Publisher's Site

2016

Effects of IL1B single nucleotide polymorphisms on depressive and anxiety symptoms are determined by severity and type of life stress.

Brain, behavior, and immunity.56():96-104[DOI] 10.1016/j.bbi.2016.02.012.[PMID] 26891860.

39 citations·PubMed·Publisher's Site

2016

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.

Diabetologia.59(8):1702-13[DOI] 10.1007/s00125-016-3973-9.[PMID] 27155871.

14 citations·PubMed·Publisher's Site

2016

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits.

Obesity (Silver Spring, Md.).24(1):51-9[DOI] 10.1002/oby.21317.[PMID] 26647900.

32 citations·PubMed·Publisher's Site

2016

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?

PloS one.11(8):e0161739-[DOI] 10.1371/journal.pone.0161739.[PMID] 27560134.

22 citations·PubMed·Publisher's Site

2016

Genetic variants of lipase activity in chronic pancreatitis.

Gut.65(1):184-5[DOI] 10.1136/gutjnl-2015-309521.[PMID] 25814649.

4 citations·PubMed·Publisher's Site

2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Nature genetics.48(12):1462-1472[DOI] 10.1038/ng.3698.[PMID] 27798627.

150 citations·PubMed·Publisher's Site

2016

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.

Diabetes.65(10):3200-11[DOI] 10.2337/db16-0199.[PMID] 27416945.

56 citations·PubMed·Publisher's Site

2016

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.

Aging cell.15(5):811-24[DOI] 10.1111/acel.12490.[PMID] 27329260.

64 citations·PubMed·Publisher's Site

2016

Genomic insights into the origin of farming in the ancient Near East.

Nature.536(7617):419-24[DOI] .[PMID] 27459054.

433 citations·PubMed·Publisher's Site

2016

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction.

Scientific reports.6():27969-[DOI] 10.1038/srep27969.[PMID] 27346320.

43 citations·PubMed·Publisher's Site

2016

Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes.

Journal of neural transmission (Vienna, Austria : 1996).123(5):541-8[DOI] 10.1007/s00702-016-1506-9.[PMID] 26821321.

29 citations·PubMed·Publisher's Site

2016

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Nature communications.7():10495-[DOI] 10.1038/ncomms10495.[PMID] 26833246.

199 citations·PubMed·Publisher's Site

2016

Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size.

International journal of obesity (2005).40(12):1832-1840[DOI] 10.1038/ijo.2016.127.[PMID] 27460604.

6 citations·PubMed·Publisher's Site

2016

Psychological side effects of immune therapies: symptoms and pathomechanism.

Current opinion in pharmacology.29():97-103[DOI] 10.1016/j.coph.2016.06.008.[PMID] 27456240.

19 citations·PubMed·Publisher's Site

2016

Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach.

Frontiers in genetics.7():102-[DOI] 10.3389/fgene.2016.00102.[PMID] 27375677.

1 citations·PubMed·Publisher's Site

2016

Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation.

Biochemical and biophysical research communications.478(1):398-402[DOI] 10.1016/j.bbrc.2016.07.038.[PMID] 27402271.

8 citations·PubMed·Publisher's Site

2016

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.

PLoS genetics.12(2):e1005874-[DOI] 10.1371/journal.pgen.1005874.[PMID] 26910538.

49 citations·PubMed·Publisher's Site

2016

The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans.

Handbook of experimental pharmacology.234():179-217[DOI] .[PMID] 27832489.

13 citations·PubMed·Publisher's Site

2015

A novel FoxD3 Variant Is Associated With Vitiligo and Elevated Thyroid Auto-Antibodies.

The Journal of clinical endocrinology and metabolism.100(10):E1335-42[DOI] 10.1210/jc.2015-2126.[PMID] 26267147.

15 citations·PubMed·Publisher's Site

2015

ADCY5 gene expression in adipose tissue is related to obesity in men and mice.

PloS one.10(3):e0120742-[DOI] 10.1371/journal.pone.0120742.[PMID] 25793868.

15 citations·PubMed·Publisher's Site

2015

Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ).

Appetite.91():241-7[DOI] 10.1016/j.appet.2015.04.044.[PMID] 25889877.

21 citations·PubMed·Publisher's Site

2015

Association between genetic variants in PNPLA3 and serum adiponectin.

Liver international : official journal of the International Association for the Study of the Liver.35(2):679-80[DOI] 10.1111/liv.12648.[PMID] 25074358.

1 citations·PubMed·Publisher's Site

2015

Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites.

PloS one.10(12):e0143190-[DOI] 10.1371/journal.pone.0143190.[PMID] 26630026.

50 citations·PubMed·Publisher's Site

2015

Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index.

PloS one.10(7):e0133977-[DOI] 10.1371/journal.pone.0133977.[PMID] 26230264.

50 citations·PubMed·Publisher's Site

2015

Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children.

PloS one.10(9):e0138064-[DOI] 10.1371/journal.pone.0138064.[PMID] 26375028.

16 citations·PubMed·Publisher's Site

2015

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Nature genetics.47(12):1415-25[DOI] 10.1038/ng.3437.[PMID] 26551672.

286 citations·PubMed·Publisher's Site

2015

Genetic studies of body mass index yield new insights for obesity biology.

Nature.518(7538):197-206[DOI] 10.1038/nature14177.[PMID] 25673413.

2876 citations·PubMed·Publisher's Site

2015

Genetic variants in AKR1B10 associate with human eating behavior.

BMC genetics.16():31-[DOI] 10.1186/s12863-015-0189-9.[PMID] 25887478.

5 citations·PubMed·Publisher's Site

2015

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.

PLoS genetics.11(9):e1005510-[DOI] 10.1371/journal.pgen.1005510.[PMID] 26401656.

32 citations·PubMed·Publisher's Site

2015

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.

Genome medicine.7():103-[DOI] 10.1186/s13073-015-0225-4.[PMID] 26449484.

88 citations·PubMed·Publisher's Site

2015

New genetic loci link adipose and insulin biology to body fat distribution.

Nature.518(7538):187-196[DOI] 10.1038/nature14132.[PMID] 25673412.

1029 citations·PubMed·Publisher's Site

2015

Noninvasive characterization of graft steatosis after liver transplantation.

Scandinavian journal of gastroenterology.50(2):224-32[DOI] 10.3109/00365521.2014.983156.[PMID] 25429378.

22 citations·PubMed·Publisher's Site

2015

Novel heterozygous IGF1R mutation in two brothers with developing impaired glucose tolerance.

Journal of pediatric endocrinology & metabolism : JPEM.28(1-2):217-25[DOI] 10.1515/jpem-2014-0132.[PMID] 25153223.

13 citations·PubMed·Publisher's Site

2015

Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.

Gut.64(9):1426-33[DOI] 10.1136/gutjnl-2014-307453.[PMID] 25253127.

80 citations·PubMed·Publisher's Site

2015

Role of genetic variants in ADIPOQ in human eating behavior.

Genes & nutrition.10(1):449-[DOI] 10.1007/s12263-014-0449-8.[PMID] 25542302.

23 citations·PubMed·Publisher's Site

2015

Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.

PloS one.10(2):e0117093-[DOI] 10.1371/journal.pone.0117093.[PMID] 25647475.

7 citations·PubMed·Publisher's Site

2015

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

PLoS genetics.11(10):e1005378-[DOI] 10.1371/journal.pgen.1005378.[PMID] 26426971.

251 citations·PubMed·Publisher's Site

2014

A central role for GRB10 in regulation of islet function in man.

PLoS genetics.10(4):e1004235-[DOI] 10.1371/journal.pgen.1004235.[PMID] 24699409.

131 citations·PubMed·Publisher's Site

2014

Adipose tissue depot specific promoter methylation of TMEM18.

Journal of molecular medicine (Berlin, Germany).92(8):881-8[DOI] 10.1007/s00109-014-1154-1.[PMID] 24763707.

16 citations·PubMed·Publisher's Site

2014

Defining the role of common variation in the genomic and biological architecture of adult human height.

Nature genetics.46(11):1173-86[DOI] 10.1038/ng.3097.[PMID] 25282103.

1181 citations·PubMed·Publisher's Site

2014

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.

International journal of obesity (2005).38(1):120-5[DOI] 10.1038/ijo.2013.56.[PMID] 23670221.

26 citations·PubMed·Publisher's Site

2014

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin.

PLoS genetics.10(12):e1004854-[DOI] 10.1371/journal.pgen.1004854.[PMID] 25521368.

28 citations·PubMed·Publisher's Site

2014

Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis.

Diabetologia.57(11):2374-83[DOI] 10.1007/s00125-014-3356-z.[PMID] 25145546.

28 citations·PubMed·Publisher's Site

2014

Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains.

Physiological genomics.46(11):377-84[DOI] 10.1152/physiolgenomics.00014.2014.[PMID] 24692188.

29 citations·PubMed·Publisher's Site

2014

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Diabetes.63(6):2158-71[DOI] 10.2337/db13-0949.[PMID] 24296717.

229 citations·PubMed·Publisher's Site

2014

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice.

Diabetes.63(10):3295-309[DOI] 10.2337/db13-0933.[PMID] 24760138.

23 citations·PubMed·Publisher's Site

2014

Serum adiponectin and progranulin levels are associated with gallstone disease.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.122(10):559-63[DOI] 10.1055/s-0034-1376969.[PMID] 25054309.

6 citations·PubMed·Publisher's Site

2014

The genetics of fat distribution.

Diabetologia.57(7):1276-86[DOI] 10.1007/s00125-014-3214-z.[PMID] 24632736.

97 citations·PubMed·Publisher's Site

2013

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.

PloS one.8(2):e56193-[DOI] 10.1371/journal.pone.0056193.[PMID] 23460794.

10 citations·PubMed·Publisher's Site

2013

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels.

Journal of molecular medicine (Berlin, Germany).91(11):1285-92[DOI] 10.1007/s00109-013-1062-9.[PMID] 23756768.

6 citations·PubMed·Publisher's Site

2013

CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?

Gut.62(4):582-92[DOI] 10.1136/gutjnl-2011-300645.[PMID] 22427236.

130 citations·PubMed·Publisher's Site

2013

Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior.

PloS one.8(9):e74362-[DOI] 10.1371/journal.pone.0074362.[PMID] 24066140.

35 citations·PubMed·Publisher's Site

2013

Contemporary paternal genetic landscape of Polish and German populations: from early medieval Slavic expansion to post-World War II resettlements.

European journal of human genetics : EJHG.21(4):415-22[DOI] 10.1038/ejhg.2012.190.[PMID] 22968131.

24 citations·PubMed·Publisher's Site

2013

Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans.

The Journal of endocrinology.216(2):135-43[DOI] 10.1530/JOE-12-0367.[PMID] 23129782.

53 citations·PubMed·Publisher's Site

2013

Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology.

Diabetologia.56(2):311-22[DOI] 10.1007/s00125-012-2773-0.[PMID] 23229156.

64 citations·PubMed·Publisher's Site

2013

Genetic analyses of bone morphogenetic protein 2, 4 and 7 in congenital combined pituitary hormone deficiency.

BMC endocrine disorders.13():56-[DOI] 10.1186/1472-6823-13-56.[PMID] 24289245.

7 citations·PubMed·Publisher's Site

2013

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.

Obesity (Silver Spring, Md.).21(12):E626-33[DOI] 10.1002/oby.20482.[PMID] 23596049.

18 citations·PubMed·Publisher's Site

2013

Genetic variants in GCKR, GIPR, ADCY5 and VPS13C and the risk of severe sulfonylurea-induced hypoglycaemia in patients with type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.121(1):54-7[DOI] 10.1055/s-0032-1321834.[PMID] 22956255.

7 citations·PubMed·Publisher's Site

2013

Genetic variation in the vaspin gene affects circulating serum vaspin concentrations.

International journal of obesity (2005).37(6):861-6[DOI] 10.1038/ijo.2012.133.[PMID] 22907691.

27 citations·PubMed·Publisher's Site

2013

Insulin administration acutely decreases vaspin serum concentrations in humans.

Obesity facts.6(1):86-8[DOI] 10.1159/000348836.[PMID] 23466514.

9 citations·PubMed·Publisher's Site

2013

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.

Obesity (Silver Spring, Md.).21(3):529-34[DOI] 10.1002/oby.20095.[PMID] 23592659.

15 citations·PubMed·Publisher's Site

2013

Role of vaspin in human eating behaviour.

PloS one.8(1):e54140-[DOI] 10.1371/journal.pone.0054140.[PMID] 23342091.

11 citations·PubMed·Publisher's Site

2013

Serum levels of acylcarnitines are altered in prediabetic conditions.

PloS one.8(12):e82459-[DOI] 10.1371/journal.pone.0082459.[PMID] 24358186.

132 citations·PubMed·Publisher's Site

2013

Serum levels of the adipokine progranulin depend on renal function.

Diabetes care.36(2):410-4[DOI] 10.2337/dc12-0220.[PMID] 23033238.

48 citations·PubMed·Publisher's Site

2013

SGLT2: a potential target for the pharmacogenetics of Type 2 diabetes?

Pharmacogenomics.14(7):825-33[DOI] 10.2217/pgs.13.61.[PMID] 23651029.

8 citations·PubMed·Publisher's Site

2013

TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs.

PloS one.8(12):e80512-[DOI] 10.1371/journal.pone.0080512.[PMID] 24312479.

42 citations·PubMed·Publisher's Site

2013

The role of rs2237781 within GRM8 in eating behavior.

Brain and behavior.3(5):495-502[DOI] 10.1002/brb3.151.[PMID] 24392270.

11 citations·PubMed·Publisher's Site

2013

THOC5: a novel gene involved in HDL-cholesterol metabolism.

Journal of lipid research.54(11):3170-6[DOI] 10.1194/jlr.M039420.[PMID] 24023261.

11 citations·PubMed·Publisher's Site

2013

Variants in CPA1 are strongly associated with early onset chronic pancreatitis.

Nature genetics.45(10):1216-20[DOI] 10.1038/ng.2730.[PMID] 23955596.

195 citations·PubMed·Publisher's Site

2013

Vaspin inhibits kallikrein 7 by serpin mechanism.

Cellular and molecular life sciences : CMLS.70(14):2569-83[DOI] 10.1007/s00018-013-1258-8.[PMID] 23370777.

100 citations·PubMed·Publisher's Site

2012

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.

PloS one.7(1):e29433-[DOI] 10.1371/journal.pone.0029433.[PMID] 22276112.

15 citations·PubMed·Publisher's Site

2012

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Nature genetics.44(6):659-69[DOI] 10.1038/ng.2274.[PMID] 22581228.

604 citations·PubMed·Publisher's Site

2012

A genome-wide association search for type 2 diabetes genes in African Americans.

PloS one.7(1):e29202-[DOI] 10.1371/journal.pone.0029202.[PMID] 22238593.

126 citations·PubMed·Publisher's Site

2012

C57BL/6JRj mice are protected against diet induced obesity (DIO).

Biochemical and biophysical research communications.417(2):717-20[DOI] 10.1016/j.bbrc.2011.12.008.[PMID] 22177950.

13 citations·PubMed·Publisher's Site

2012

Fat mass and obesity-associated (fto) gene and alcohol intake.

Addiction (Abingdon, England).107(6):1185-6[DOI] 10.1111/j.1360-0443.2012.03825.x.[PMID] 22509951.

6 citations·PubMed·Publisher's Site

2012

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.

PloS one.7(5):e37981-[DOI] 10.1371/journal.pone.0037981.[PMID] 22666428.

5 citations·PubMed·Publisher's Site

2012

Genetics of adiponectin.

Biochimie.94(10):2157-63[DOI] 10.1016/j.biochi.2012.03.004.[PMID] 22449616.

34 citations·PubMed·Publisher's Site

2012

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

Nature genetics.44(9):991-1005[DOI] 10.1038/ng.2385.[PMID] 22885924.

622 citations·PubMed·Publisher's Site

2012

Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein.

International journal of obesity (2005).36(6):766-73[DOI] 10.1038/ijo.2011.162.[PMID] 21863005.

19 citations·PubMed·Publisher's Site

2012

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.

Diabetes.61(5):1291-6[DOI] 10.2337/db11-0973.[PMID] 22415877.

21 citations·PubMed·Publisher's Site

2012

Substantial increase in incidence of severe hypoglycemia between 1997-2000 and 2007-2010: a German longitudinal population-based study.

Diabetes care.35(5):972-5[DOI] 10.2337/dc11-1470.[PMID] 22410817.

45 citations·PubMed·Publisher's Site

2012

The Ser1369Ala variant of ABCC8 and the risk for severe sulfonylurea-induced hypoglycemia in German patients with Type 2 diabetes.

Pharmacogenomics.13(1):5-7; author reply 9[DOI] 10.2217/pgs.11.150.[PMID] 22176616.

13 citations·PubMed·Publisher's Site

2011

Association and evolutionary studies of the melatonin receptor 1B gene (MTNR1B) in the self-contained population of Sorbs from Germany.

Diabetic medicine : a journal of the British Diabetic Association.28(11):1373-80[DOI] 10.1111/j.1464-5491.2011.03374.x.[PMID] 21711391.

12 citations·PubMed·Publisher's Site

2011

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects.

Diabetologia.54(7):1819-23[DOI] 10.1007/s00125-011-2137-1.[PMID] 21465327.

107 citations·PubMed·Publisher's Site

2011

Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes.

Journal of proteome research.10(10):4769-88[DOI] 10.1021/pr2005555.[PMID] 21823675.

153 citations·PubMed·Publisher's Site

2011

Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.

PloS one.6(7):e22101-[DOI] 10.1371/journal.pone.0022101.[PMID] 21789219.

21 citations·PubMed·Publisher's Site

2011

Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts.

BMC medical genetics.12():149-[DOI] 10.1186/1471-2350-12-149.[PMID] 22093174.

8 citations·PubMed·Publisher's Site

2011

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.

PloS one.6(2):e16155-[DOI] 10.1371/journal.pone.0016155.[PMID] 21311592.

34 citations·PubMed·Publisher's Site

2011

Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity.

European journal of human genetics : EJHG.19(9):995-1001[DOI] 10.1038/ejhg.2011.65.[PMID] 21559053.

51 citations·PubMed·Publisher's Site

2011

Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays.

BMC genetics.12():67-[DOI] 10.1186/1471-2156-12-67.[PMID] 21798003.

21 citations·PubMed·Publisher's Site

2011

Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82.

PloS one.6(12):e29400-[DOI] 10.1371/journal.pone.0029400.[PMID] 22216272.

16 citations·PubMed·Publisher's Site

2011

Retinol binding protein 4 (RBP4) is primarily associated with adipose tissue mass in children.

International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity.6(2-2):e345-52[DOI] 10.3109/17477166.2010.491228.[PMID] 20950077.

42 citations·PubMed·Publisher's Site

2011

Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis.

Pharmacogenomics.12(8):1119-26[DOI] 10.2217/pgs.11.69.[PMID] 21830867.

29 citations·PubMed·Publisher's Site

2011

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.

Human molecular genetics.20(10):2071-7[DOI] 10.1093/hmg/ddr086.[PMID] 21357676.

94 citations·PubMed·Publisher's Site

2011

TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes.

BMC medical genetics.12():30-[DOI] 10.1186/1471-2350-12-30.[PMID] 21349175.

47 citations·PubMed·Publisher's Site

2011

The effect of ACACB cis-variants on gene expression and metabolic traits.

PloS one.6(8):e23860-[DOI] 10.1371/journal.pone.0023860.[PMID] 21887335.

22 citations·PubMed·Publisher's Site

2011

The promoter variant -803 G>A in the RBP4 gene is not associated with BMI, metabolic parameters or blood pressure in Caucasian children.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.119(10):628-32[DOI] 10.1055/s-0031-1286295.[PMID] 22068556.

5 citations·PubMed·Publisher's Site

2011

Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children.

International journal of obesity (2005).35(4):578-86[DOI] 10.1038/ijo.2010.196.[PMID] 20856257.

56 citations·PubMed·Publisher's Site

2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Nature genetics.42(11):937-48[DOI] 10.1038/ng.686.[PMID] 20935630.

2121 citations·PubMed·Publisher's Site

2010

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.

European journal of human genetics : EJHG.18(1):104-10[DOI] 10.1038/ejhg.2009.107.[PMID] 19584900.

70 citations·PubMed·Publisher's Site

2010

Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].10(2-3):243-9[DOI] 10.1159/000243769.[PMID] 20484962.

7 citations·PubMed·Publisher's Site

2010

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

Diabetes.59(5):1266-75[DOI] 10.2337/db09-1568.[PMID] 20185807.

197 citations·PubMed·Publisher's Site

2010

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression.

Obesity (Silver Spring, Md.).18(6):1218-25[DOI] 10.1038/oby.2009.392.[PMID] 19876008.

17 citations·PubMed·Publisher's Site

2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Nature genetics.42(2):142-8[DOI] 10.1038/ng.521.[PMID] 20081857.

487 citations·PubMed·Publisher's Site

2010

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

PLoS genetics.6(11):e1001213-[DOI] 10.1371/journal.pgen.1001213.[PMID] 21124955.

21 citations·PubMed·Publisher's Site

2010

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Nature.467(7317):832-8[DOI] 10.1038/nature09410.[PMID] 20881960.

1386 citations·PubMed·Publisher's Site

2010

Insulin-sensitive obesity.

American journal of physiology. Endocrinology and metabolism.299(3):E506-15[DOI] 10.1152/ajpendo.00586.2009.[PMID] 20570822.

585 citations·PubMed·Publisher's Site

2010

Involvement of the chemokine-like receptor GPR33 in innate immunity.

Biochemical and biophysical research communications.396(2):272-7[DOI] 10.1016/j.bbrc.2010.04.077.[PMID] 20399748.

6 citations·PubMed·Publisher's Site

2010

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Nature genetics.42(11):949-60[DOI] 10.1038/ng.685.[PMID] 20935629.

701 citations·PubMed·Publisher's Site

2010

Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis.

Pancreas.39(2):188-92[DOI] 10.1097/MPA.0b013e3181bd94ae.[PMID] 19959969.

3 citations·PubMed·Publisher's Site

2010

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Nature genetics.42(2):105-16[DOI] 10.1038/ng.520.[PMID] 20081858.

1666 citations·PubMed·Publisher's Site

2010

New loci associated with kidney function and chronic kidney disease.

Nature genetics.42(5):376-84[DOI] 10.1038/ng.568.[PMID] 20383146.

633 citations·PubMed·Publisher's Site

2010

Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections.

PloS one.5(5):e10882-[DOI] 10.1371/journal.pone.0010882.[PMID] 20526368.

37 citations·PubMed·Publisher's Site

2010

Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia.

Metabolism: clinical and experimental.59(7):1054-6[DOI] 10.1016/j.metabol.2009.11.001.[PMID] 20045145.

28 citations·PubMed·Publisher's Site

2010

Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes.

Biochemical and biophysical research communications.400(2):246-51[DOI] 10.1016/j.bbrc.2010.08.049.[PMID] 20727851.

22 citations·PubMed·Publisher's Site

2010

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.

Pharmacogenomics.11(5):693-702[DOI] 10.2217/pgs.10.42.[PMID] 20415562.

14 citations·PubMed·Publisher's Site

2010

Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].10(2-3):165-72[DOI] 10.1159/000231979.[PMID] 20460947.

1 citations·PubMed·Publisher's Site

2010

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Nature genetics.42(5):448-53[DOI] 10.1038/ng.573.[PMID] 20418888.

539 citations·PubMed·Publisher's Site

2010

Serum vaspin concentrations are decreased after exercise-induced oxidative stress.

Obesity facts.3(5):328-31[DOI] 10.1159/000321637.[PMID] 20975299.

23 citations·PubMed·Publisher's Site

2010

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

PLoS genetics.6(4):e1000916-[DOI] 10.1371/journal.pgen.1000916.[PMID] 20421936.

232 citations·PubMed·Publisher's Site

2009

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.

Diabetes.58(9):2119-28[DOI] 10.2337/db08-1458.[PMID] 19502417.

62 citations·PubMed·Publisher's Site

2009

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.

Human molecular genetics.18(23):4662-8[DOI] 10.1093/hmg/ddp423.[PMID] 19729412.

57 citations·PubMed·Publisher's Site

2009

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

Nature genetics.41(2):157-9[DOI] 10.1038/ng.301.[PMID] 19151714.

486 citations·PubMed·Publisher's Site

2009

MicroRNA expression in human omental and subcutaneous adipose tissue.

PloS one.4(3):e4699-[DOI] 10.1371/journal.pone.0004699.[PMID] 19259271.

254 citations·PubMed·Publisher's Site

2009

The E23K variant of KCNJ11 and the risk for severe sulfonylurea-induced hypoglycemia in patients with type 2 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.41(5):387-90[DOI] 10.1055/s-0029-1192019.[PMID] 19214942.

41 citations·PubMed·Publisher's Site

2009

Vaspin serum concentrations in patients with carotid stenosis.

Atherosclerosis.204(1):262-6[DOI] 10.1016/j.atherosclerosis.2008.08.028.[PMID] 18848328.

76 citations·PubMed·Publisher's Site

2008

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.

Nature genetics.40(1):78-82[DOI] .[PMID] 18059268.

274 citations·PubMed·Publisher's Site

2008

Common nonsynonymous variants in PCSK1 confer risk of obesity.

Nature genetics.40(8):943-5[DOI] 10.1038/ng.177.[PMID] 18604207.

217 citations·PubMed·Publisher's Site

2008

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.

Diabetologia.51(4):641-7[DOI] 10.1007/s00125-008-0928-9.[PMID] 18251005.

83 citations·PubMed·Publisher's Site

2008

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.

PloS one.3(12):e3852-[DOI] 10.1371/journal.pone.0003852.[PMID] 19052638.

12 citations·PubMed·Publisher's Site

2008

Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene.

European journal of endocrinology.159(2):129-36[DOI] 10.1530/EJE-08-0220.[PMID] 18469018.

46 citations·PubMed·Publisher's Site

2008

Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1beta/maturity-onset diabetes of the young type 5 gene.

Metabolism: clinical and experimental.57(3):416-20[DOI] 10.1016/j.metabol.2007.11.001.[PMID] 18249217.

9 citations·PubMed·Publisher's Site

2008

Polygenic contribution to obesity: genome-wide strategies reveal new targets.

Frontiers of hormone research.36():12-36[DOI] 10.1159/000115335.[PMID] 18230892.

25 citations·PubMed·Publisher's Site

2008

R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians.

Journal of human genetics.53(4):365-367[DOI] 10.1007/s10038-008-0252-8.[PMID] 18231709.

15 citations·PubMed·Publisher's Site

2008

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.

Metabolism: clinical and experimental.57(9):1227-31[DOI] 10.1016/j.metabol.2008.04.016.[PMID] 18702948.

14 citations·PubMed·Publisher's Site

2008

Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans.

Journal of hepatology.48(1):116-24[DOI] .[PMID] 17931734.

69 citations·PubMed·Publisher's Site

2007

A SNP haplotype of the forkhead transcription factor FOXO1A gene may have a protective effect against type 2 diabetes in German Caucasians.

Diabetes & metabolism.33(4):277-83[DOI] .[PMID] 17555999.

15 citations·PubMed·Publisher's Site

2007

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.

Diabetes.56(12):3095-100[DOI] .[PMID] 17728376.

76 citations·PubMed·Publisher's Site

2007

Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children.

Metabolism: clinical and experimental.56(6):772-7[DOI] .[PMID] 17512309.

20 citations·PubMed·Publisher's Site

2007

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.

Diabetologia.50(7):1472-80[DOI] .[PMID] 17492427.

174 citations·PubMed·Publisher's Site

2007

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.

Cell metabolism.6(1):79-87[DOI] .[PMID] 17618858.

309 citations·PubMed·Publisher's Site

2007

Sex-specific effect of the Val1483Ile polymorphism in the fatty acid synthase gene (FAS) on body mass index and lipid profile in Caucasian children.

International journal of obesity (2005).31(2):353-8[DOI] .[PMID] 16788566.

20 citations·PubMed·Publisher's Site

2007

TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children.

The Journal of clinical endocrinology and metabolism.92(5):1956-60[DOI] .[PMID] 17311858.

30 citations·PubMed·Publisher's Site

2007

Variation in FTO contributes to childhood obesity and severe adult obesity.

Nature genetics.39(6):724-6[DOI] .[PMID] 17496892.

1165 citations·PubMed·Publisher's Site

2006

A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo.

Diabetes.55(5):1497-503[DOI] .[PMID] 16644711.

12 citations·PubMed·Publisher's Site

2006

ENPP1 variants and haplotypes predispose to early onset obesity and impaired glucose and insulin metabolism in German obese children.

The Journal of clinical endocrinology and metabolism.91(12):4948-52[DOI] .[PMID] 16968801.

42 citations·PubMed·Publisher's Site

2006

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.

The Journal of clinical endocrinology and metabolism.91(7):2725-31[DOI] .[PMID] 16636125.

55 citations·PubMed·Publisher's Site

2006

The insertion/deletion polymorphism in the angiotensin-converting enzyme gene and hypoglycemia awareness in patients with type 1 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.38(9):603-6[DOI] .[PMID] 16981144.

8 citations·PubMed·Publisher's Site

2006

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.

Biochemical and biophysical research communications.339(1):430-6[DOI] .[PMID] 16298335.

250 citations·PubMed·Publisher's Site

2005

[Genetics of type 2 diabetes].

Der Internist.46(7):741-2, 744[DOI] .[PMID] 15912330.

2 citations·PubMed·Publisher's Site

2005

Fatty acids and insulin resistance in muscle and liver.

Best practice & research. Clinical endocrinology & metabolism.19(4):625-35[DOI] .[PMID] 16311221.

93 citations·PubMed·Publisher's Site

2005

Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.

Diabetologia.48(11):2292-5[DOI] .[PMID] 16167150.

39 citations·PubMed·Publisher's Site

2005

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.

Diabetes.54(10):2911-6[DOI] .[PMID] 16186392.

531 citations·PubMed·Publisher's Site

2005

The Glu23Lys polymorphism in KCNJ11 and impaired hypoglycaemia awareness in patients with type 1 diabetes.

Journal of human genetics.50(10):530-533[DOI] 10.1007/s10038-005-0288-y.[PMID] 16142506.

3 citations·PubMed·Publisher's Site

2004

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.

Diabetes.53(7):1915-9[DOI] .[PMID] 15220220.

42 citations·PubMed·Publisher's Site

2004

Ultrasound-guided lumbar facet nerve block: accuracy of a new technique confirmed by computed tomography.

Anesthesiology.101(5):1195-200[DOI] .[PMID] 15505456.

78 citations·PubMed·Publisher's Site

2003

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians.

Diabetes.52(5):1292-5[DOI] .[PMID] 12716768.

28 citations·PubMed·Publisher's Site

2003

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.

Diabetes.52(6):1544-50[DOI] .[PMID] 12765968.

37 citations·PubMed·Publisher's Site

2001

Suppression of melanoma cell proliferation by histidine decarboxylase specific antisense oligonucleotides.

The Journal of investigative dermatology.117(1):151-3[DOI] .[PMID] 11442763.

48 citations·PubMed·Publisher's Site

1998

A protocol-contract for opioid use in patients with chronic pain not due to malignancy.

Journal of clinical anesthesia.10(5):435-43[DOI] .[PMID] 9702628.

12 citations·PubMed·Publisher's Site

1989

Insulin imprinting of neuroblastoma cells.

Cell biology international reports.13(6):563-7[DOI] .[PMID] 2670250.

PubMed·Publisher's Site

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