Sophia S. Sheikh, M.D.

Sophia S. Sheikh M.D.

Associate Professor

Department: Department of Emergency Medicine
Business Phone: (904) 244-4986
Business Email: Sophia.sheikh@jax.ufl.edu

About Sophia S. Sheikh

Sophia Sheikh, M.D., received her degree from the University of Alabama School of Medicine at Birmingham and completed her residency training at the University of Florida School of Medicine – Jacksonville. She then pursued further training in the field of medical toxicology at the joint program offered by Emory University and the Centers for Disease Control and Prevention in Atlanta, Georgia. While learning the clinical aspects of medical toxicology, she also learned principles related to public health surveillance, epidemiology, public health and disease prevention. In addition to toxicology, she also has an interest in emergency department pain management. She is a sub-investigator on a patient safety grant working on improving pain management and education in acute care settings. She authored several publications and presented lectures nationally on these topics. Currently, she is a clinical assistant professor at the University of Florida School of Medicine – Jacksonville.

Clinical Profile

Specialties
  • Emergency Medicine
  • Medical Toxicology
Interests
  • Clinical Special Interests: Medical toxicology
  • Research Special Interests: Medical toxicology

Publications

2024
Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals.
Psychological medicine.54(2):338-349[DOI] 10.1017/S0033291723001642.[PMID] 37309917.
2024
Author Correction: Defining the r factor for post-trauma resilience and its neural predictors
Nature Mental Health.2(5):627-627[DOI] 10.1038/s44220-024-00258-6.[PMID] .
2024
Characterizing Utilization and Outcomes of Digoxin Immune Fab for Digoxin Toxicity
Drugs - Real World Outcomes.11(3):377-388[DOI] 10.1007/s40801-024-00435-0.[PMID] 38839728.
2024
Defining the r factor for post-trauma resilience and its neural predictors
Nature Mental Health.2(6):680-693[DOI] 10.1038/s44220-024-00242-0.[PMID] .
2024
Disentangling sex differences in PTSD risk factors
Nature Mental Health.2(5):605-615[DOI] 10.1038/s44220-024-00236-y.[PMID] 39534178.
2024
Emergency department management of North American snake envenomations.
Emergency medicine practice.26(Suppl 2):1-44[DOI] .[PMID] 38350100.
2024
Heart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure
Psychiatry Research.342():116260-[DOI] 10.1016/j.psychres.2024.116260.[PMID] .
2024
Intensive longitudinal assessment following index trauma to predict development of PTSD using machine learning.
Journal of anxiety disorders.104():102876-[DOI] 10.1016/j.janxdis.2024.102876.[PMID] 38723405.
2024
Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma.
JAMA psychiatry.81(11):1090-1100[DOI] 10.1001/jamapsychiatry.2024.2148.[PMID] 39083325.
2024
Oral varespladib for the treatment of snakebite envenoming in India and the USA (BRAVO): a phase II randomised clinical trial
BMJ Global Health.9(10):e015985-[DOI] 10.1136/bmjgh-2024-015985.[PMID] 39442939.
2024
Probing the neurocardiac circuit in trauma and posttraumatic stress
Journal of Psychiatric Research.176():173-181[DOI] 10.1016/j.jpsychires.2024.06.009.[PMID] 38875773.
2024
Psychedelic mushroom-containing chocolate exposures: Case series.
The American journal of emergency medicine.85():208-213[DOI] 10.1016/j.ajem.2024.09.038.[PMID] 39288500.
2024
Sex Differences in Response Inhibition-Related Neural Predictors of Posttraumatic Stress Disorder in Civilians With Recent Trauma.
Biological psychiatry. Cognitive neuroscience and neuroimaging.9(7):668-680[DOI] 10.1016/j.bpsc.2024.03.002.[PMID] 38522649.
2024
Sex-dependent differences in vulnerability to early risk factors for posttraumatic stress disorder: results from the AURORA study.
Psychological medicine.():1-11[DOI] 10.1017/S0033291724000941.[PMID] 38775091.
2023
A pilot study to identify pharmacogenomic and clinical risk factors associated with opioid related falls and adverse effects in older adults
Clinical and Translational Science.16(11):2331-2344[DOI] 10.1111/cts.13634.[PMID] 37705211.
2023
Association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure
Translational Psychiatry.13(1):-[DOI] 10.1038/s41398-023-02643-8.[PMID] 37980332.
2023
Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision.
Annals of emergency medicine.81(3):249-261[DOI] 10.1016/j.annemergmed.2022.08.011.[PMID] 36328855.
2023
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure
Molecular Psychiatry.28(12):5140-5149[DOI] 10.1038/s41380-023-02012-3.[PMID] 36932158.
2023
Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma.
JAMA network open.6(9):e2334483-[DOI] 10.1001/jamanetworkopen.2023.34483.[PMID] 37721751.
2023
Prior Sexual Trauma Exposure Impacts Posttraumatic Dysfunction and Neural Circuitry Following a Recent Traumatic Event in the AURORA Study.
Biological psychiatry global open science.3(4):705-715[DOI] 10.1016/j.bpsgos.2023.02.004.[PMID] 37881578.
2023
Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Molecular Psychiatry.28(7):2975-2984[DOI] 10.1038/s41380-023-01971-x.[PMID] 36725899.
2023
Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort
Translational Psychiatry.13(1):-[DOI] 10.1038/s41398-022-02289-y.[PMID] 36609484.
2022
Anxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study
Journal of Psychiatric Research.156():45-54[DOI] 10.1016/j.jpsychires.2022.09.027.[PMID] 36242943.
2022
Characterizing OPRM1 DNA methylation in prescription opioid users with chronic musculoskeletal pain.
Pain reports.7(6):e1046-[DOI] 10.1097/PR9.0000000000001046.[PMID] .
2022
Hippocampal Threat Reactivity Interacts with Physiological Arousal to Predict PTSD Symptoms.
The Journal of neuroscience : the official journal of the Society for Neuroscience.42(34):6593-6604[DOI] 10.1523/JNEUROSCI.0911-21.2022.[PMID] 35879096.
2022
Neurocognition after motor vehicle collision and adverse post-traumatic neuropsychiatric sequelae within 8 weeks: Initial findings from the AURORA study.
Journal of affective disorders.298(Pt B):57-67[DOI] 10.1016/j.jad.2021.10.104.[PMID] 34800569.
2022
Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure.
The American journal of psychiatry.179(9):661-672[DOI] 10.1176/appi.ajp.21090911.[PMID] 35730162.
2022
Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study
PLOS ONE.17(9):e0273378-[DOI] 10.1371/journal.pone.0273378.[PMID] 36149896.
2022
Prior histories of posttraumatic stress disorder and major depression and their onset and course in the three months after a motor vehicle collision in the AURORA study.
Depression and anxiety.39(1):56-70[DOI] 10.1002/da.23223.[PMID] 34783142.
2022
Structural covariance of the ventral visual stream predicts posttraumatic intrusion and nightmare symptoms: a multivariate data fusion analysis
Translational Psychiatry.12(1):-[DOI] 10.1038/s41398-022-02085-8.[PMID] 35941117.
2022
Validating the HELP Survey to Understand Health Disparity Influence on Chronic Pain.
Journal of pain research.15():545-560[DOI] 10.2147/JPR.S338669.[PMID] 35228818.
2021
A prospective examination of sex differences in posttraumatic autonomic functioning
Neurobiology of Stress.15():100384-[DOI] 10.1016/j.ynstr.2021.100384.[PMID] 34485632.
2021
Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma.
The American journal of psychiatry.178(11):1037-1049[DOI] 10.1176/appi.ajp.2021.20101526.[PMID] 34645277.
2021
Classification and Prediction of Post-Trauma Outcomes Related to PTSD Using Circadian Rhythm Changes Measured via Wrist-Worn Research Watch in a Large Longitudinal Cohort
IEEE Journal of Biomedical and Health Informatics.25(8):2866-2876[DOI] 10.1109/jbhi.2021.3053909.[PMID] .
2021
Comparing Pain Intensity Using the Numeric Rating Scale and Defense and Veterans Pain Rating Scale in Patients Revisiting the Emergency Department.
Cureus.13(8):e17501-[DOI] 10.7759/cureus.17501.[PMID] 34603880.
2021
Development and Validation of a Model to Predict Posttraumatic Stress Disorder and Major Depression After a Motor Vehicle Collision.
JAMA psychiatry.78(11):1228-1237[DOI] 10.1001/jamapsychiatry.2021.2427.[PMID] 34468741.
2021
Opioid Overdose Risk in Patients Returning to the Emergency Department for Pain
Pain Medicine.22(9):2100-2105[DOI] 10.1093/pm/pnab047.[PMID] 33560418.
2021
Pain after a motor vehicle crash: The role of socio‐demographics, crash characteristics and peri‐traumatic stress symptoms
European Journal of Pain.25(5):1119-1136[DOI] 10.1002/ejp.1733.[PMID] .
2021
Prior sleep problems and adverse post-traumatic neuropsychiatric sequelae of motor vehicle collision in the AURORA study
Sleep.44(3):-[DOI] 10.1093/sleep/zsaa200.[PMID] 32975289.
2021
Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study
Neuropsychopharmacology.46(7):1263-1271[DOI] 10.1038/s41386-020-00946-8.[PMID] 33479509.
2021
Socio-demographic and trauma-related predictors of PTSD within 8 weeks of a motor vehicle collision in the AURORA study
Molecular Psychiatry.26(7):3108-3121[DOI] 10.1038/s41380-020-00911-3.[PMID] 33077855.
2021
Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity
Journal of Psychiatric Research.141():325-332[DOI] 10.1016/j.jpsychires.2021.07.023.[PMID] 34304036.
2021
The Toxicology Investigators Consortium 2020 Annual Report
Journal of Medical Toxicology.17(4):333-362[DOI] 10.1007/s13181-021-00854-3.[PMID] 34535889.
2020
Predicting Pain-Related 30-Day Emergency Department Return Visits in Middle-Aged and Older Adults
Pain Medicine.21(11):2748-2756[DOI] 10.1093/pm/pnaa213.[PMID] 32875332.
2020
Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study.
Psychological medicine.():1-14[DOI] 10.1017/S0033291720003773.[PMID] 33118917.
2019
Risk Factors Associated with Emergency Department Recidivism in the Older Adult.
The western journal of emergency medicine.20(6):931-938[DOI] 10.5811/westjem.2019.7.43073.[PMID] 31738721.
2018
Emergency department management of North American snake envenomations.
Emergency medicine practice.20(9):1-26[DOI] .[PMID] 30130010.
2018
Points & Pearls: Emergency department management of North American snake envenomations.
Emergency medicine practice.20(19 Suppl):1-2[DOI] .[PMID] 30179413.
2018
The Expanding Role of Ketamine in the Emergency Department
Drugs.78(7):727-735[DOI] 10.1007/s40265-018-0904-8.[PMID] .
2017
Female With Vaginal Spotting.
Annals of emergency medicine.70(1):e1-e2[DOI] 10.1016/j.annemergmed.2017.01.012.[PMID] 28645417.
2016
Assessing patient activation and health literacy in the ED.
The American journal of emergency medicine.34(1):93-6[DOI] 10.1016/j.ajem.2015.09.045.[PMID] 26508580.
2016
Response to Comments on "Poisonings with Suicidal Intent Aged 0-21 Years Reported to Poison Centers 2003-12".
The western journal of emergency medicine.17(1):94-6[DOI] 10.5811/westjem.2015.12.29429.[PMID] 26823943.
2015
Poisonings with Suicidal Intent Aged 0-21 Years Reported to Poison Centers 2003-12.
The western journal of emergency medicine.16(4):497-502[DOI] 10.5811/westjem.2015.5.25459.[PMID] 26265960.
2014
Comparison of Iatrogenic Adverse Drug Events Occurring in Hospital and Community Settings Reported To Three Poison Centers
Clinical Toxicology.52(7):691-692[DOI] .[PMID] .
2014
Incidents of potential public health significance identified using national surveillance of US poison center data (2008–2012)
Clinical Toxicology.52(9):958-963[DOI] 10.3109/15563650.2014.953171.[PMID] 25175899.
2013
Characterizing risk factors for pediatric lamp oil product exposures
Clinical Toxicology.51(9):871-878[DOI] 10.3109/15563650.2013.839028.[PMID] 24066734.
2013
Passive Multistate Surveillance for Neutropenia After Use of Cocaine or Heroin Possibly Contaminated With Levamisole
Annals of Emergency Medicine.61(4):468-474[DOI] 10.1016/j.annemergmed.2012.10.036.[PMID] .
2012
Do-Not-Resuscitate Orders in Fatal Toxic Exposures: A Poison Center's Review.
The western journal of emergency medicine.13(3):294-7[DOI] 10.5811/westjem.2012.3.11725.[PMID] 22928059.
2012
Exotic venomous snakebite drill
Clinical Toxicology.50(6):490-496[DOI] 10.3109/15563650.2012.690882.[PMID] .
2012
Radiological preparedness-awareness and attitudes: A cross–sectional survey of emergency medicine residents and physicians at three academic institutions in the United States
Clinical Toxicology.50(1):34-38[DOI] 10.3109/15563650.2011.637047.[PMID] .

Office Information

Academic Office
1st Floor, Clinical Center
655 West 8th Street
Jacksonville, FL 32209
(904) 244-4986
Sophia.sheikh@jax.ufl.edu
Executive Assistant
Amy Kennedy
(904) 244-4986
amy.kennedy@jax.ufl.edu

Education

Medical Degree
2007 · University of Alabama School of Medicine, Birmingham, AL, USA
Emergency Medicine Residency
2010 · University of Florida College of Medicine-Jacksonville, Jacksonville, FL, USA
Medical Toxicology Fellowship
2012 · Emory University School of Medicine, Atlanta, GA, USA