Francisco J. Martinez-Wittinghan, M.D., Ph.D.

Francisco J. Martinez-Wittinghan M.D., Ph.D.

Assistant Professor & Medical Director, UF Health Family Medicine - Augustine Oaks

Department: Department of Community Health and Family Medicine
Business Phone: (904) 383-1970

About Francisco J. Martinez-Wittinghan

Francisco Martinez-Wittinghan, M.D., Ph.D., has been a family physician in North Florida for more than 11 years. He was born in Colombia, South America, and graduated from the Universidad del Rosario’s Medical School in 1995. He moved to Stony Brook, New York, where he earned his doctorate in physiology and biophysics.

Dr. Martinez-Wittinghan worked a few years as a researcher and returned to clinical work in the family residency program at Long Island Jewish Medical Center. During his last year of training, he was elected chief resident by his peers and program director.

He is passionate about improving quality, team-based care and is currently completing his master's degree in health sciences informatics through the Johns Hopkins School of Medicine. He believes that technology should be used to improve patient care and decrease the burden to health care professionals.

Dr. Martinez-Wittinghan's unique training helps him focus on finding the cause, not just masking the symptoms of disease. He bases patient care on prevention and lifestyle changes that can have a lasting effect on health. He is very compassionate and enjoys counseling, teaching and listening to his patients. His areas of expertise include management of asthma, diabetes, habit modification, hypertension and preventive care.

He and his family enjoy being involved with the community, bicycling, hiking, going to the beach and walking their dogs.

Martin-Wittinghan speaks English and Spanish.

Clinical Profile

  • Family Medicine
  • Speaks English and Spanish


Study protocol for a type III hybrid effectiveness-implementation trial to evaluate scaling interoperable clinical decision support for patient-centered chronic pain management in primary care.
Implementation science : IS.17(1):44-[DOI] 10.1186/s13012-022-01217-4.[PMID] 35841043.
PKCγ, role in lens differentiation and gap junction coupling.
Current eye research.36(7):620-31[DOI] 10.3109/02713683.2011.573899.[PMID] 21599470.
The effects of GPX-1 knockout on membrane transport and intracellular homeostasis in the lens.
The Journal of membrane biology.227(1):25-37[DOI] 10.1007/s00232-008-9141-5.[PMID] 19067024.
Mefloquine effects on the lens suggest cooperative gating of gap junction channels.
The Journal of membrane biology.211(3):163-71[DOI] .[PMID] 17091216.
Connections between connexins, calcium, and cataracts in the lens.
The Journal of general physiology.124(4):289-300[DOI] .[PMID] 15452195.
Lens gap junctional coupling is modulated by connexin identity and the locus of gene expression.
Investigative ophthalmology & visual science.45(10):3629-37[DOI] .[PMID] 15452070.
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
The Journal of cell biology.161(5):969-78[DOI] .[PMID] 12782682.
Gap junctional coupling in lenses from alpha(8) connexin knockout mice.
The Journal of general physiology.118(5):447-56[DOI] .[PMID] 11696604.

Office Information

Academic Office
1255 Lila Street
Jacksonville, FL 32208
(904) 383-1001
Office Manager
Seraphin Lindor
(904) 383-1970


Medical Degree
Universidad del Rosario, Bogota, Columbia
Medical Degree
The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ph.D., Physiology and Biophysics
2002 · State University of New York, Stony Brook, NY, USA
Family Medicine Residency
2009 · North Shore-Long Island Jewish Health System, New Hyde Park, NY, USA